Environmental risk factors of rhinitis in early infancy.

Environmental risk factors of rhinitis in early infancy. Research Abstract Details 

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Environmental risk factors of rhinitis in early infancy. Abstract Text:

Jocelyn M Biagini,Grace K LeMasters,Patrick H Ryan,Linda Levin,Tiina Reponen,David I Bernstein,Manuel Villareal,Gurjit K Khurana Hershey,Jeffrey Burkle,James Lockey,

Previous studies of allergic rhinitis in children have not documented the environmental risk factors for infants at age one. We examined the relationship of environmental tobacco smoke (ETS) and visible mold exposures on the development of allergic rhinitis, rhinitis and upper respiratory infection (URI) in a birth cohort where at least one parent was skin prick test (SPT) positive. ETS exposure and upper respiratory symptoms were obtained by questionnaires. Visible mold was classified as none, low or high during home visit. Infants had a SPT at age one. After adjustment for potential confounders, exposure to >20 cigarettes per day was associated with an increased risk of developing allergic rhinitis at age one [odds ratio (OR)=2.7; 95% CI 1.04-6.8] and rhinitis symptoms during the first year (OR=1.9; 95% CI 1.1-3.2). Infants with low (OR=1.5; 95% CI 1.1-2.3) or high (OR=5.1; 95% CI 2.2-12.1) levels of visible mold in their homes were more likely to have more frequent URI during the first year. Older siblings were protective for development of both rhinitis symptoms and allergic rhinitis. This study suggests that ETS exposure, rather than visible mold, is associated with rhinitis and allergic rhinitis in infants. The analysis also suggests that mold may be a stronger risk factor for URI that ETS.

Environmental risk factors of rhinitis in early infancy. Publishing Authors By Initials

JM Biagini,GK LeMasters,PH Ryan,L Levin,T Reponen,DI Bernstein,M Villareal,GK Khurana Hershey,J Burkle,J Lockey,

For similar complex mixtures: particulate matter: smoke: tobacco smoke pollution research abstracts see: complex mixtures: particulate matter: smoke: tobacco smoke pollution research

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Environmental risk factors of rhinitis in early infancy. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Pediatric allergy and immunology : official public

VOLUME: 17

Page Numbers: 278-84

Journal Abbreviation:

ISSN: 0905-6157

DAY: 11

MONTH: Jun

YEAR: 2006

Environmental risk factors of rhinitis in early infancy. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9106718

Environmental risk factors of rhinitis in early infancy. Keywords Mesh Terms:

KEYWORDS: Tobacco Smoke Pollution

MESH TERMS: statistics & numerical data

Chemical & Substance for Abstract: Environmental risk factors of rhinitis in early infancy. Information

Substance Name: Tobacco Smoke Pollution

Registry Number: 0

Grant and Affiliation Information for Environmental risk factors of rhinitis in early infancy.

AFFILIATION: Department of Environmental Health, University of Cincinnati, and Division of Allergy and Immunology, Department of Pediatrics, Cincinati Children's Hospital Medical Center, OH 45267-0056, USA. biaginjm@email.uc.edu

Country: England

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MEDLINETA: Pediatr Allergy Immunol

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