Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity.

Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity. Abstract Text:

N Kubo,T Minami,Y Hori,T Yamashita,T Kumazawa,

In order to verify the role of cholinergic nerves in nasal allergy and nonspecific nasal hypersensitivity we have evaluated the muscarinic acetylcholine receptors and the activity of choline acetyltransferase in nasal mucosa of TDI-sensitized guinea-pigs at specific points in time during a pre-determined sensitization period. The density of muscarinic receptors was significantly elevated in animals sensitized for 8 and/or 12 weeks as well as in the group which received 12 weeks of sensitization followed by a 4 week rest period. Choline acetyltransferase activity was also enhanced at 4-, 8- and 12 weeks. These observations provide biochemical evidence of the hyperactivity of cholinergic nerves in nasal allergy which has been suggested by clinical and pharmacological studies, and lead to the speculation that enhanced parasympathetic nerve function is implicated in causing and maintaining hypersensitivity and hypersecretion in nasal allergy.

Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity. Publishing Authors By Initials

N Kubo,T Minami,Y Hori,T Yamashita,T Kumazawa,

For similar organic chemicals: hydrocarbons: hydrocarbons, cyclic: hydrocarbons, aromatic: benzene derivatives: toluene: toluene 2,4-diisocyanate research abstracts see: organic chemicals: hydrocarbons: hydrocarbons, cyclic: hydrocarbons, aromatic: benzene derivatives: toluene: toluene 2,4-diisocyanate research

PUBMED ID PMID:

MEDLINE DATE:

Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Acta oto-laryngologica. Supplementum

VOLUME: 463

Page Numbers: 14-20

Journal Abbreviation:

ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 1989

Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370355

Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity. Keywords Mesh Terms:

KEYWORDS: Toluene 2,4-Diisocyanate

MESH TERMS: metabolism

Chemical & Substance for Abstract: Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity. Information

Substance Name: Choline O-Acetyltransferase

Registry Number: EC 2.3.1.6

Grant and Affiliation Information for Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity.

AFFILIATION: Department of Otolaryngology, Kansai Medical University, Osaka, Japan.

Country: SWEDEN

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Acta Otolaryngol Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity Related Publications

• A possible masking effect of tinnitus. Evaluation of CNV audiometry.
• Active opening function of the human eustachian tube: comparison between sonotubometry and pressure equilibration test.
• Approach to the diagnosis of sialadenosis using sialography.
• Autonomic nervous system in human palatine tonsil.
• Effects of acetazolamide on acid-base balance in the endolymphatic sac of the guinea pig.
• Effects of efferent neurotransmitters on intracellular Ca2+ concentration in vestibular hair cells of the guinea pig.
• Effects of miglitol, an alpha-glucosidase inhibitor, on glycaemic status and histopathological changes in islets in non-obese, non-insulin-dependent diabetic Goto-Kakizaki rats.
• Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity.
• Establishment of a cisplatin-resistant KB cell line and its characterization.
• Experimental and clinical evaluation of DNA ploidy with use of double staining of keratin/DNA by flow cytometer in head and neck tumor.
• Functional disturbances of the sympathetic nerve in experimentally-induced nasal hypersensitivity.
• Head and neck reconstruction with microvascular tissue transfer and its surgical indications: our experiences. A review.
• Histamine and acetylcholine regulation of sympathetic nerve activity in guinea-pig nasal mucosa.
• Histamine content and histamine H1 receptor in experimentally-induced nasal hypersensitivity.
• Kinetics of epidermal growth factor in saliva.
• Menière's disease and autoimmunity: clinical study and survey.
• Middle ear ventilation mechanism.
• Molecular phylogenetic and dating analyses using mitochondrial DNA sequences of eyelid geckos (Squamata: Eublepharidae).
• Norepinephrine content in guinea-pig nasal mucosa response to histamine and methacholine provocation.
• Otitis media with effusion and eustachian tube dysfunction in adults and children.
• Otitis media with effusion and tubal tonsil (video).
• Participation of autonomic nerve in tonsillar focal infection.
• Recent activities in otolaryngology -- head and neck surgery. Dedicated to Professor Tadami Kumazawa.
• Regulation of Cl- conductance in delayed shortening and shrinkage of outer hair cells.
• Subjective results of laser surgery for allergic rhinitis.
• Surgical anatomy for infralabyrinthine approach to the internal auditory canal.
• The tonsillar immune system: its response to exogenous antigens.
• The usefulness of partial parotidectomy for benign parotid gland tumors. A retrospective study of 306 cases.
• Thermal influence on intracellular calcium concentration in vestibular hair cells isolated from the guinea pig. A preliminary report.
• Thyroid follicle transplantation by percutaneous injection.