Enhanced diffusion weighting generated by selective adiabatic pulse trains.

Enhanced diffusion weighting generated by selective adiabatic pulse trains. Research Abstract Details 

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Enhanced diffusion weighting generated by selective adiabatic pulse trains. Abstract Text:

Ziqi Sun,Robert Bartha,

A theoretical description and experimental validation of the enhanced diffusion weighting generated by selective adiabatic full passage (AFP) pulse trains is provided. Six phantoms (Ph-1-Ph-6) were studied on a 4 T Varian/Siemens whole body MRI system. Phantoms consisted of 2.8 cm diameter plastic tubes containing a mixture of 10 microm ORGASOL polymer beads and 2mM Gd-DTPA dissolved in 5% agar (Ph-1) or nickel(II) ammonium sulphate hexahydrate doped (56.3-0.8 mM) water solutions (Ph-2-Ph-6). A customized localization by adiabatic selective refocusing (LASER) sequence containing slice selective AFP pulse trains and pulsed diffusion gradients applied in the phase encoding direction was used to measure (1)H(2)O diffusion. The b-value associated with the LASER sequence was derived using the Bloch-Torrey equation. The apparent diffusion coefficients measured by LASER were comparable to those measured by a conventional pulsed gradient spin-echo (PGSE) sequence for all phantoms. Image signal intensity increased in Ph-1 and decreased in Ph-2-Ph-6 as AFP pulse train length increased while maintaining a constant echo-time. These experimental results suggest that such AFP pulse trains can enhance contrast between regions containing microscopic magnetic susceptibility variations and homogeneous regions in which dynamic dephasing relaxation mechanisms are dominant.

Enhanced diffusion weighting generated by selective adiabatic pulse trains. Publishing Authors By Initials

Z Sun,R Bartha,

For similar equipment and supplies: phantoms, imaging research abstracts see: equipment and supplies: phantoms, imaging research

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Enhanced diffusion weighting generated by selective adiabatic pulse trains. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of magnetic resonance (San Diego, Calif. :

VOLUME: 188

Page Numbers: 35-40

Journal Abbreviation: J. Magn. Reson.

ISSN: 1090-7807

DAY: 9

MONTH: 06

YEAR: 2007

Enhanced diffusion weighting generated by selective adiabatic pulse trains. Information

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LANGUAGE: eng

NlmUniqueID: 9707935

Enhanced diffusion weighting generated by selective adiabatic pulse trains. Keywords Mesh Terms:

KEYWORDS: Phantoms, Imaging

MESH TERMS: methods

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Grant and Affiliation Information for Enhanced diffusion weighting generated by selective adiabatic pulse trains.

AFFILIATION: Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada.

Country: United States

AGENCY: United States NIBIB

GRANT: R01-EB001852

ACRONYM: EB

MEDLINETA: J Magn Reson

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