Endovascular electrocoagulation: concept, technique, and experimental results.

Endovascular electrocoagulation: concept, technique, and experimental results. Research Abstract Details 

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Endovascular electrocoagulation: concept, technique, and experimental results. Abstract Text:

C Ji,G Guglielmi,H Chen,

PURPOSE: To evaluate the safety and efficacy of an embolotherapeutic technique that uses electrolytically detachable platinum coils and radio frequency (RF) energy to achieve rapid and distal occlusion of targeted vessels. METHODS: In swine, branches of the ascending cervical artery and the hepatic artery measuring 1.5 mm or less were subjected to endovascular electrocoagulation. RF energy was delivered through modified Guglielmi detachable platinum coils that were placed in the targeted arteries. Ohmic heating generated by RF caused vessel occlusion. After the vessel occlusions were confirmed angiographically, the platinum microcoils were electrolytically detached from the delivery wire and left in the vessels as implants. RESULTS: All vessels were rapidly and superselectively occluded by endovascular electrocoagulation. Following use of the appropriate methods derived from this research, we did not observe rupture of the artery, dissection of the artery, unintended occlusion, or migration of the platinum microcoil. Histologic examination of treated vessels at 6 and 12 weeks revealed obliteration of the vessel lumen by the platinum microcoil surrounded by granulation tissue. CONCLUSION: Endovascular electrocoagulation is a rapid method of achieving vessel occlusion. It may be a useful and controllable embolotherapeutic technique when expeditious occlusion of small vessels and distal superselectivity are desired.

Endovascular electrocoagulation: concept, technique, and experimental results. Publishing Authors By Initials

C Ji,G Guglielmi,H Chen,

For similar diagnosis: prognosis: treatment outcome research abstracts see: diagnosis: prognosis: treatment outcome research

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Endovascular electrocoagulation: concept, technique, and experimental results. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: AJNR. American journal of neuroradiology

VOLUME: 18

Page Numbers: 1669-78

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ISSN: 0195-6108

DAY: 14

MONTH: Oct

YEAR: 1997

Endovascular electrocoagulation: concept, technique, and experimental results. Information

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LANGUAGE: eng

NlmUniqueID: 8003708

Endovascular electrocoagulation: concept, technique, and experimental results. Keywords Mesh Terms:

KEYWORDS: Treatment Outcome

MESH TERMS: instrumentation

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Grant and Affiliation Information for Endovascular electrocoagulation: concept, technique, and experimental results.

AFFILIATION: Leo G. Rigler Center for Radiological Research, University of California at Los Angeles Medical School, USA.

Country: UNITED STATES

AGENCY: United States NHLBI

GRANT: 5 R01 HL46286-04

ACRONYM: HL

MEDLINETA: AJNR Am J Neuroradiol

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