Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience.

Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience. Research Abstract Details 

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Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience. Abstract Text:

Dipti Anand,Julieta E Barroeta,Prabodh K Gupta,Michael Kochman,Zubair W Baloch,Dipti Anand,Julieta E Barroeta,Prabodh K Gupta,Michael Kochman,Zubair W Baloch,

BACKGROUND: Endoscopic ultrasound guided fine needle aspiration biopsy (EUS-FNA) has proven to be an effective diagnostic modality for the detection and staging of pancreatic malignancies. In recent years EUS-FNA has also been used to diagnose lesions of non-pancreatic sites such as structures in close proximity to the gut wall within the mediastinum, abdomen, pelvis and retro-peritoneum. AIMS: To evaluate experience with EUS-FNA of non-pancreatic sites at a large university medical centre. METHODS: The study cohort included 234 patients who underwent EUS-FNA of 246 lesions in non-pancreatic sites (122 peri-pancreatic and coeliac lymph nodes; 9 peri-pancreatic masses; other sites: mediastinum 12, gastric 25, liver 27, oesophagus 17, duodenum/colon/rectum 15, retro-peritoneum 8, lung 7, miscellaneous 4). RESULTS: The cytology diagnoses were classified as non-neoplastic/reactive in 82 (33%), atypical/suspicious for malignancy in 25 (10%), malignant in 86 (35%) and non-diagnostic in 53 (22%) cases. Surgical pathology follow-up was available in 75 (31%) cases. Excluding the non-diagnostic cases there were 7 false negative and 3 false positive cases. The sensitivity, specificity and positive predictive value of EUS-FNA in the diagnosis of lesions of non-pancreatic sites was 92%, 98% and 97%, respectively. CONCLUSIONS: EUS-FNA can be effectively used as a diagnostic modality in the diagnosis of lesions from non-pancreatic sites.

Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience. Publishing Authors By Initials

D Anand,JE Barroeta,PK Gupta,M Kochman,ZW Baloch,D Anand,JE Barroeta,PK Gupta,M Kochman,ZW Baloch,

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Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of clinical pathology

VOLUME: 60

Page Numbers: 1254-62

Journal Abbreviation: J. Clin. Pathol.

ISSN: 1472-4146

DAY: 12

MONTH: 01

YEAR: 2007

Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience.

AFFILIATION: Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA.

Country: England

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MEDLINETA: J Clin Pathol

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