Endogenous synthesis of coenzyme Q in eukaryotes.

Endogenous synthesis of coenzyme Q in eukaryotes. Research Abstract Details 

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Endogenous synthesis of coenzyme Q in eukaryotes. Abstract Text:

UyenPhuong C Tran,Catherine F Clarke,

Coenzyme Q (Q) functions in the mitochondrial respiratory chain and serves as a lipophilic antioxidant. There is increasing interest in the use of Q as a nutritional supplement. Although, the physiological significance of Q is extensively investigated in eukaryotes, ranging from yeast to human, the eukaryotic Q biosynthesis pathway is best characterized in the budding yeast Saccharomyces cerevisiae. At least ten genes (COQ1-COQ10) have been shown to be required for Q biosynthesis and function in respiration. This review highlights recent knowledge about the endogenous synthesis of Q in eukaryotes, with emphasis on S. cerevisiae as a model system.

Endogenous synthesis of coenzyme Q in eukaryotes. Publishing Authors By Initials

UC Tran,CF Clarke,

For similar organic chemicals: quinones: benzoquinones: ubiquinone research abstracts see: organic chemicals: quinones: benzoquinones: ubiquinone research

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Endogenous synthesis of coenzyme Q in eukaryotes. Journal Published:

PUBLICATION TYPE: Review

Journal: Mitochondrion

VOLUME: 7 Suppl

Page Numbers: S62-71

Journal Abbreviation: Mitochondrion

ISSN: 1567-7249

DAY: 30

MONTH: 03

YEAR: 2007

Endogenous synthesis of coenzyme Q in eukaryotes. Information

Number of References: 100

LANGUAGE: eng

NlmUniqueID: 100968751

Endogenous synthesis of coenzyme Q in eukaryotes. Keywords Mesh Terms:

KEYWORDS: Ubiquinone

MESH TERMS: metabolism

Chemical & Substance for Abstract: Endogenous synthesis of coenzyme Q in eukaryotes. Information

Substance Name: Carbon

Registry Number: 7440-44-0

Grant and Affiliation Information for Endogenous synthesis of coenzyme Q in eukaryotes.

AFFILIATION: Department of Chemistry and Biochemistry, Molecular Biology Institute, University of California, 607 Charles E. Young Drive East, Los Angeles, CA 90095-1569, USA.

Country: Netherlands

AGENCY: United States NIGMS

GRANT: GM45952

ACRONYM: GM

MEDLINETA: Mitochondrion

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