Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4.

Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4. Abstract Text:

K Katano,Y Hayatsu,T Matsuda,R Miyazaki,K Yamada,M Kawano,N Takahashi,H Kimura,H Yoshida,K Katano,Y Hayatsu,T Matsuda,R Miyazaki,K Yamada,M Kawano,N Takahashi,H Kimura,H Yoshida,

Renal lesions of IgG4-related disease have been reported recently. Most of them are tubulointerstitial nephritis, and a definite glomerulonephritis complicating IgG4-related disease is very rare. We report here a case of definite glomerulonephritis and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4. A 68-year-old Japanese woman was referred to our hospital for investigation of anasarca. We diagnosed her disease as a nephrotic syndrome and left hydroureteronephrosis due to retroperitoneal fibrosis. Her laboratory data revealed a high serum level of IgG4, renal injury, hypoproteinemia, hypocomplementemia, a positive finding of circulating immunocomplex (CIC), and negative findings ofautologous antibodies suggesting systemic lupus erythematosus (SLE) or Sjögren's syndrome (SS). A diagnosis of SLE or SS could not be made clinically. Right renal biopsy revealed endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis. Infiltration of plasma cells in interstitium was more conspicuous than seen with ordinary tubulointerstitial nephritis, and in most of them IgG4 was positive. We placed a percutaneous nephrostomy catheter in her left kidney, and prescribed prednisolone and cyclosporine. The responses to prednisolone and cyclosporine therapies were very good. Further studies are needed to clarify the relationship between glomerulonephritis and IgG4-related disease. However, when considering renal lesions of IgG4-related disease, we think that hypocomplementemia, a positive finding of CIC, negative findings of autologous antibodies suggesting SLE or SS, conspicuous interstitial infiltration of IgG4-positive plasma cells, and a good response to steroid or immunosuppressant therapy are key points.

Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4. Publishing Authors By Initials

K Katano,Y Hayatsu,T Matsuda,R Miyazaki,K Yamada,M Kawano,N Takahashi,H Kimura,H Yoshida,K Katano,Y Hayatsu,T Matsuda,R Miyazaki,K Yamada,M Kawano,N Takahashi,H Kimura,H Yoshida,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical nephrology

VOLUME: 68

Page Numbers: 308-14

Journal Abbreviation: Clin. Nephrol.

ISSN: 0301-0430

DAY: 29

MONTH: Nov

YEAR: 2007

Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 364441

Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4.

AFFILIATION: Department of Internal Medicine, Fujita Memorial Hospital, Fukui, Japan. yukaken@p2332.nsk.ne.jp

Country: Germany

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Clin Nephrol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Endocapillary proliferative glomerulonephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG4 Related Publications

• "Watermelon rectum" associated with multiple vascular ectasia in the colon.
• A compact UHV X-ray diffractometer for studying surfaces and interfaces.
• Abnormal course of the oculomotor nerve on the clivus combined with a petroclival meningioma: case report.
• Application of independent component analysis and expansion matching filter for automatic detection of motor unit action potential trains.
• Application of near-infrared spectroscopy to measuring of attractiveness of opposite-sex faces.
• Binding sites on laminin receptors as components for antibiotics.
• CYP17 polymorphism and tamoxifen-induced hepatic steatosis.
• Chromosomal abnormalities subdivide neuroepithelial tumors into clinically relevant groups.
• Clear cell hidradenoma of the breast: a case report with review of the literature.
• Clinical characteristics of hypotonia: a survey of pediatric physical and occupational therapists.
• Detection of high concentrations of 137Cs in Walleye pollock collected in the Sea of Japan.
• Efficacy of recombinant annexin 2 for fibrinolytic therapy in a rat embolic stroke model: a magnetic resonance imaging study.
• Electrochemical generation of glycosyl triflate pools.
• Electron microscopic examination of the dormant spore and the sporulation of Paenibacillus motobuensis strain MC10.
• Experimental and analytical investigations of motor unit location for the precise estimation of muscle force with surface electromyograms.
• F1-ATPase rotates by an asymmetric, sequential mechanism using all three catalytic subunits.
• Feasibility of oxaliplatin and infusional fluorouracil/leucovorin (FOLFOX4) for Japanese patients with unresectable metastatic colorectal cancer.
• Fully Automated Three-Dimensional Detection of Polyps in Fecal-Tagging CT Colonography.
• Iatrogenic perforation associated with therapeutic colonoscopy: a multicenter study in Japan.
• Insufficient outcomes with imatinib mesylate: case report of Ph-positive acute myeloid leukemia evolving from myelodysplastic syndrome.
• Interferential current stimulation for sensory communication between prosthetic hand and man.
• Neuropsin promotes oligodendrocyte death, demyelination and axonal degeneration after spinal cord injury.
• Photoactivated ethidium monoazide directly cleaves bacterial DNA and is applied to PCR for discrimination of live and dead bacteria.
• Protein kinase C delta activates IkappaB-kinase alpha to induce the p53 tumor suppressor in response to oxidative stress.
• Recovery of olfactory function after an anterior craniofacial approach.
• Retrospective review of pediatric and adult autoimmune hepatitis in two quaternary care centres in British Columbia: increased prevalence seen in British Columbia's First Nations community.
• STUDIES ON THE EXPRESSION LEVELS OF STEROL-METABOLIZING ENZYMES IN THE OBESE MODEL SHR/NDmcr-cp RATS.
• Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.
• Surface modification of poly(ethylene terephthalate) by plasma polymerization of poly(ethylene glycol).
• Varicella zoster virus meningoencephalitis accompanied by sporadic skin lesions in an older immunocompetent adult.