Endemic eastern equine encephalitis in the Amazon region of Peru.

Endemic eastern equine encephalitis in the Amazon region of Peru. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Endemic eastern equine encephalitis in the Amazon region of Peru. Abstract Text:

Patricia V Aguilar,Rebecca M Robich,Michael J Turell,Monica L O'Guinn,Terry A Klein,Alfredo Huaman,Carolina Guevara,Zonia Rios,Robert B Tesh,Douglas M Watts,James Olson,Scott C Weaver,

Eastern equine encephalitis virus (EEEV) causes severe neurologic disease in North America, but only two fatal human cases have been documented in South America. To test the hypothesis that alphavirus heterologous antibodies cross-protect, animals were vaccinated against other alphaviruses and challenged up to 3 months later with EEEV. Short-lived cross-protection was detected, even in the absence of cross-neutralizing antibodies. To assess exposure to EEEV in Peru, sera from acutely ill and healthy persons were tested for EEEV and other alphavirus antibodies, as well as for virus isolation. No EEEV was isolated from patients living in an EEEV-enzootic area, and only 2% of individuals with febrile illness had EEEV-reactive IgM. Only 3% of healthy persons from the enzootic region had EEEV-neutralizing antibodies. Our results suggest that humans are exposed but do not develop apparent infection with EEEV because of poor infectivity and/or avirulence of South American strains.

Endemic eastern equine encephalitis in the Amazon region of Peru. Publishing Authors By Initials

PV Aguilar,RM Robich,MJ Turell,ML O'Guinn,TA Klein,A Huaman,C Guevara,Z Rios,RB Tesh,DM Watts,J Olson,SC Weaver,

For similar investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: seroepidemiologic studies research abstracts see: investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: seroepidemiologic studies research

PUBMED ID PMID:

MEDLINE DATE:

Endemic eastern equine encephalitis in the Amazon region of Peru. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: The American journal of tropical medicine and hygi

VOLUME: 76

Page Numbers: 293-8

Journal Abbreviation: Am. J. Trop. Med. Hyg.

ISSN: 0002-9637

DAY: 3

MONTH: Feb

YEAR: 2007

Endemic eastern equine encephalitis in the Amazon region of Peru. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370507

Endemic eastern equine encephalitis in the Amazon region of Peru. Keywords Mesh Terms:

KEYWORDS: Seroepidemiologic Studies

MESH TERMS: epidemiology

Chemical & Substance for Abstract: Endemic eastern equine encephalitis in the Amazon region of Peru. Information

Substance Name: Antibodies, Viral

Registry Number: 0

Grant and Affiliation Information for Endemic eastern equine encephalitis in the Amazon region of Peru.

AFFILIATION: Center for Biodefense and Emerging Infectious Diseases, Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas 77555-0609, USA.

Country: United States

AGENCY: United States NIAID

GRANT: AI049725

ACRONYM: AI

MEDLINETA: Am J Trop Med Hyg

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Endemic eastern equine encephalitis in the Amazon region of Peru Related Publications

• A distal conserved sequence element controls Ifng gene expression by T cells and NK cells.
• Accessing and recruiting children for research in schools.
• Adherence to positive airway pressure therapy.
• Alterations of T lymphocytes in inflammatory bowel diseases.
• Comparison of anatomic, physiological, and subjective measures of the nasal airway.
• Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia.
• Deforestation alters phytotelm habitat availability and mosquito production in the Peruvian Amazon.
• Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis.
• Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock.
• Diffusion-controlled mean reaction times in biological systems with elliptical symmetry.
• Emerging plasmid-encoded antisense RNA regulated systems.
• Endemic eastern equine encephalitis in the Amazon region of Peru.
• Feasibility of an electrode-reservoir device for transdermal drug delivery by noninvasive skin electroporation.
• Infection and dissemination of Venezuelan equine encephalitis virus in the epidemic mosquito vector, Aedes taeniorhynchus.
• Invadopodia: specialized cell structures for cancer invasion.
• Lead-related nephrotoxicity: a review of the epidemiologic evidence.
• Light-induced phase shifts in mice lacking mPER1 or mPER2.
• Membrane electroporation: The absolute rate equation and nanosecond time scale pore creation.
• Organic dairy production systems in Pennsylvania: a case study evaluation.
• Photic induction of Period gene expression is reduced in Clock mutant mice.
• Potential of ancestral sylvatic dengue-2 viruses to re-emerge.
• Racial differences in skeletal calcium retention in adolescent girls with varied controlled calcium intakes.
• Reverse transcription-PCR-enzyme-linked immunosorbent assay for rapid detection and differentiation of alphavirus infections.
• Serologic evidence of widespread everglades virus activity in dogs, Florida.
• Serotonin 5-HT(2C) receptor homodimerization is not regulated by agonist or inverse agonist treatment.
• Sleep rhythmicity and homeostasis in mice with targeted disruption of mPeriod genes.
• Soy isoflavones do not affect bone resorption in postmenopausal women: a dose-response study using a novel approach with 41Ca.
• Targeted disruption of the mPer3 gene: subtle effects on circadian clock function.
• The cellular inflammatory response in human spinal cords after injury.
• Transient, light-induced rhythmicity in mPer-deficient mice.