Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: confirmation of stereostructure by x-ray analysis.

Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: confirmation of stereostructure by x-ray analysis. Research Abstract Details 

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Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: confirmation of stereostructure by x-ray analysis. Abstract Text:

Tingyou Li,Yuko Tsuda,Katsuhiko Minoura,Yasuko In,Toshimasa Ishida,Lawrence H Lazarus,Yoshio Okada,

Six phenylalanine analogues containing 2'-methyl-, 2',6'-dimethyl-, 2'-ethyl-6'-methyl-, 2'-isopropyl-6'-methyl-, 2',4',6'-trimethyl-, and 3',5'-dimethyl-L-phenylalanine were synthesized enantioselectively through asymmetric hydrogenation of acetamidoacrylate derivatives. Enzymatic digestion and X-ray analysis supported the L-configuration of the phenylalanine derivatives obtained.

Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: confirmation of stereostructure by x-ray analysis. Publishing Authors By Initials

T Li,Y Tsuda,K Minoura,Y In,T Ishida,LH Lazarus,Y Okada,

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Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: confirmation of stereostructure by x-ray analysis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Chemical & pharmaceutical bulletin

VOLUME: 54

Page Numbers: 873-7

Journal Abbreviation: Chem. Pharm. Bull.

ISSN: 0009-2363

DAY: 6

MONTH: Jun

YEAR: 2006

Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: confirmation of stereostructure by x-ray analysis. Information

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LANGUAGE: eng

NlmUniqueID: 377775

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Grant and Affiliation Information for Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: confirmation of stereostructure by x-ray analysis.

AFFILIATION: The Graduate School of Food and Medicinal Sciences and Faculty of Pharmaceutical Sciences, Kobe Gakuin University.

Country: Japan

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MEDLINETA: Chem Pharm Bull (Tokyo)

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