Enantiomeric separation of beta2-agonists on macrocyclic antibiotic chiral stationary phases in high performance liquid chromatography.

Enantiomeric separation of beta2-agonists on macrocyclic antibiotic chiral stationary phases in high performance liquid chromatography. Research Abstract Details 

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Enantiomeric separation of beta2-agonists on macrocyclic antibiotic chiral stationary phases in high performance liquid chromatography. Abstract Text:

Dandan Zhang,Maosheng Cheng,Myung Ho Hyun,Zhili Xiong,Li Pan,Famei Li,Dandan Zhang,Maosheng Cheng,Myung Ho Hyun,Zhili Xiong,Li Pan,Famei Li,

The enantiomeric resolution of six beta2-agonists including bambuterol, clenbuterol, clenproperol, fumoterol, mabuterol and terbutaline, was studied on three macrocyclic antibiotic chiral stationary phases (CSPs): Chirobiotic V, T and R. By varying the mobile phase compositions for different CSPs, all the six compounds were successfully separated on Chirobiotic V and T CSPs. The thermodynamic parameter variation was calculated. The chiral recognition mechanism was discussed, the ionic interaction was confirmed to be the most dramatic interaction responsible for the chiral recognition. No enantiosepartion for all the beta2-agonists was found on Chirobiotic R CSP.

Enantiomeric separation of beta2-agonists on macrocyclic antibiotic chiral stationary phases in high performance liquid chromatography. Publishing Authors By Initials

D Zhang,M Cheng,MH Hyun,Z Xiong,L Pan,F Li,D Zhang,M Cheng,MH Hyun,Z Xiong,L Pan,F Li,

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Enantiomeric separation of beta2-agonists on macrocyclic antibiotic chiral stationary phases in high performance liquid chromatography. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Die Pharmazie

VOLUME: 62

Page Numbers: 836-40

Journal Abbreviation: Pharmazie

ISSN: 0031-7144

DAY: 10

MONTH: Nov

YEAR: 2007

Enantiomeric separation of beta2-agonists on macrocyclic antibiotic chiral stationary phases in high performance liquid chromatography. Information

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LANGUAGE: eng

NlmUniqueID: 9800766

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Grant and Affiliation Information for Enantiomeric separation of beta2-agonists on macrocyclic antibiotic chiral stationary phases in high performance liquid chromatography.

AFFILIATION: Department of Analytical Chemistry, Shenyang Pharmaceutical University, Shen-yang, China. dandanzhang625@hotmail.com

Country: Germany

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MEDLINETA: Pharmazie

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