Emerging methods in proteomics: top-down protein characterization by multistage tandem mass spectrometry.

Emerging methods in proteomics: top-down protein characterization by multistage tandem mass spectrometry. Research Abstract Details 

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Emerging methods in proteomics: top-down protein characterization by multistage tandem mass spectrometry. Abstract Text:

Gwynyth Scherperel,Gavin E Reid,

"Top-down" mass spectrometry methods have emerged as an attractive alternative to conventional "bottom-up" approaches for the comprehensive characterization of co- and post-translational protein modifications. Here we present a brief overview of current strategies employed for top-down protein characterization and discuss the key technical challenges and solutions associated with their implementation on a range of mass spectrometry instrument platforms. For more specific details regarding the individual strategies described herein, interested readers are referred to the references cited at the end of this article.

Emerging methods in proteomics: top-down protein characterization by multistage tandem mass spectrometry. Publishing Authors By Initials

G Scherperel,GE Reid,

For similar investigative techniques: chemistry, analytical: mass spectrometry: tandem mass spectrometry research abstracts see: investigative techniques: chemistry, analytical: mass spectrometry: tandem mass spectrometry research

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Emerging methods in proteomics: top-down protein characterization by multistage tandem mass spectrometry. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Analyst

VOLUME: 132

Page Numbers: 500-6

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ISSN: 0003-2654

DAY: 10

MONTH: 04

YEAR: 2007

Emerging methods in proteomics: top-down protein characterization by multistage tandem mass spectrometry. Information

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LANGUAGE: eng

NlmUniqueID: 372652

Emerging methods in proteomics: top-down protein characterization by multistage tandem mass spectrometry. Keywords Mesh Terms:

KEYWORDS: Tandem Mass Spectrometry

MESH TERMS: methods

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Registry Number: 0

Grant and Affiliation Information for Emerging methods in proteomics: top-down protein characterization by multistage tandem mass spectrometry.

AFFILIATION: Department of Chemistry, Michigan State University, 234 Chemistry Building, East Lansing, MI 48824, USA.

Country: England

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MEDLINETA: Analyst

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