Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease.

Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease. Abstract Text:

Chronic kidney disease (CKD) increases cardiovascular risk and mortality. However, traditional cardiovascular risk factors do not adequately account for the substantial increase in mortality observed in CKD. The aim of this study was to examine the relative contributions of novel cardiovascular risk factors to the risk between CKD and mortality. The study population included 4,680 consecutive new patients from a tertiary care preventive cardiology program from 1996 to 2005. Estimated glomerular filtration rate was calculated using the Modification of Diet in Renal Disease (MDRD) method. Baseline levels of traditional (low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, hypertension, triglycerides, total cholesterol, and fasting glucose) and emerging (apolipoproteins A-I and B, lipoprotein[a], fibrinogen, homocysteine, and high-sensitivity C-reactive protein) risk factors were examined. All-cause mortality was obtained from the Social Security Death Index. There were 278 deaths over a median follow-up period of 22 months. CKD (estimated glomerular filtration rate /=12.5 mumol/L (the top tertile) were associated with a sevenfold greater mortality risk. In conclusion, homocysteine and fibrinogen levels explain nearly 40% of the attributable mortality risk from CKD.

Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The American journal of cardiology

VOLUME: 101

Page Numbers: 1741-6

Journal Abbreviation: Am. J. Cardiol.

ISSN: 0002-9149

DAY: 9

MONTH: 04

YEAR: 2008

Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 207277

Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease.

AFFILIATION: Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio; Center for Cardiovascular Diagnostics and Prevention, Cleveland Clinic Foundation, Cleveland, Ohio.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Am J Cardiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease Related Publications

• Activation of antifungal extracts of actinomycetes by ultrafiltration through gradocol membranes.
• Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study.
• Carbamazepine induces mitotic arrest in mammalian Vero cells.
• Characterization of oxidative pathways in chronic rhinosinusitis and sinonasal polyposis.
• Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages.
• Conformation of an endogenous ligand in a membrane bilayer for the macrophage scavenger receptor CD36.
• Corrigendum: The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction.
• Corrigendum: The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction.
• Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure.
• Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease.
• Gender differences in utilization of effective cardiovascular secondary prevention: a cleveland clinic prevention database study.
• Glutamate surface speciation on amorphous titanium dioxide and hydrous ferric oxide.
• Hemodynamics influences vascular peroxynitrite formation: Implication for low-density lipoprotein apo-B-100 nitration.
• In vitro assessment of the cytotoxic and mutagenic potential of perfluorooctanoic acid.
• Indices for the measurement of gingival inflammation in clinical studies of oral hygiene and periodontal disease.
• Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction.
• Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells.
• Oxidized phospholipids as endogenous pattern recognition ligands in innate immunity.
• Phospholipid hydroxyalkenals, a subset of recently discovered endogenous CD36 ligands, spontaneously generate novel furan-containing phospholipids lacking CD36 binding activity in vivo.
• Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.
• Protein carbamylation links inflammation, smoking, uremia and atherogenesis.
• Relation of keratosis seborrheica and keratosis senilis to vitamin A deficiency.
• Relationship of Paraoxonase 1 (PON1) Gene Polymorphisms and Functional Activity With Systemic Oxidative Stress and Cardiovascular Risk.
• Rocky Mountain Spotted Fever in New York State Outside of New York City.
• Scrubbing Reimbursement Rates clean.
• The distribution of soil microorganisms antagonistic to fungi pathogenic for man.
• The lipid whisker model of the structure of oxidized cell membranes.
• The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction.
• What cancer control dollars did in 1947 in Indiana.
• [OBJECTIVES OF THE DESIGNS FOR WATER SUPPLY SYSTEMS.]