Embryonic loss in pony mares induced by intrauterine infusion of Candida parapsilosis.

Embryonic loss in pony mares induced by intrauterine infusion of Candida parapsilosis. Research Abstract Details 

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Embryonic loss in pony mares induced by intrauterine infusion of Candida parapsilosis. Abstract Text:

B A Ball,S J Shin,V H Patten,M C Garcia,G L Woods,

Pony mares which were detected pregnant by transrectal ultrasonography received a single intrauterine infusion of either sterile saline (control, n = 12 mares) or 10(6)Candida parapsilosis (treated, n = 12 mares) between Days 11 to 14 postovulation. Subsequent embryonic loss was studied by daily ultrasonography of the mare's uterus, by serum progesterone levels, by endometrial swabs for cytologic and microbiologic examination and by endometrial biopsies that were taken after embryonic loss was detected. Significantly fewer (P<0.01) embryonic losses occurred in control than in treated mares (4 12 vs 12 12 ). The mean interval from intrauterine infusion until embryonic loss was 5.8 +/- 2.8 d for control mares (n = 4) and 2.1 +/- 0.2 d for treated mares (n = 12). Prior to embryonic loss, moderate to marked edema of the endometrial folds in 12 of 12 treated mares and free fluid in the uterine lumen of 5 of 12 treated mares were detected by ultrasonography. After embryonic loss, Candida parapsilosis was cultured from the uteri of 8 of 12 treated mares, and E . coli was cultured from the uteri of 2 of 4 control mares. Postloss endometrial smears had cytologic evidence of inflammation in 10 of 12 treated mares and 3 of 4 control mares. Intrauterine inoculation of C. parapsilosis consistently induced embryonic loss and may provide a basis to further study the relationship between endometritis and embryonic loss in mares.

Embryonic loss in pony mares induced by intrauterine infusion of Candida parapsilosis. Publishing Authors By Initials

BA Ball,SJ Shin,VH Patten,MC Garcia,GL Woods,

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Embryonic loss in pony mares induced by intrauterine infusion of Candida parapsilosis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Theriogenology

VOLUME: 29

Page Numbers: 835-47

Journal Abbreviation: Theriogenology

ISSN: 0093-691X

DAY: 26

MONTH: Apr

YEAR: 1988

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LANGUAGE: eng

NlmUniqueID: 421510

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Grant and Affiliation Information for Embryonic loss in pony mares induced by intrauterine infusion of Candida parapsilosis.

AFFILIATION: Department of Clinical Sciences New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.

Country: United States

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MEDLINETA: Theriogenology

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