EMAGE Edinburgh Mouse Atlas of Gene Expression: 2008 update.

EMAGE Edinburgh Mouse Atlas of Gene Expression: 2008 update. Research Abstract Details 

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EMAGE Edinburgh Mouse Atlas of Gene Expression: 2008 update. Abstract Text:

Shanmugasundaram Venkataraman,Peter Stevenson,Yiya Yang,Lorna Richardson,Nicholas Burton,Thomas P Perry,Paul Smith,Richard A Baldock,Duncan R Davidson,Jeffrey H Christiansen,Shanmugasundaram Venkataraman,Peter Stevenson,Yiya Yang,Lorna Richardson,Nicholas Burton,Thomas P Perry,Paul Smith,Richard A Baldock,Duncan R Davidson,Jeffrey H Christiansen,

EMAGE (http://genex.hgu.mrc.ac.uk/Emage/database) is a database of in situ gene expression patterns in the developing mouse embryo. Domains of expression from raw data images are spatially integrated into a set of standard 3D virtual mouse embryos at different stages of development, allowing data interrogation by spatial methods. Sites of expression are also described using an anatomy ontology and data can be queried using text-based methods. Here we describe recent enhancements to EMAGE which include advances in spatial search methods including: a refined local spatial similarity search algorithm, a method to allow global spatial comparison of patterns in EMAGE and subsequent hierarchical-clustering, and spatial searches across multiple stages of development. In addition, we have extended data access by the introduction of web services and new HTML-based search interfaces, which allow access to data that has not yet been spatially annotated. We have also started incorporating full 3D images of gene expression that have been generated using optical projection tomography (OPT).

EMAGE Edinburgh Mouse Atlas of Gene Expression: 2008 update. Publishing Authors By Initials

S Venkataraman,P Stevenson,Y Yang,L Richardson,N Burton,TP Perry,P Smith,RA Baldock,DR Davidson,JH Christiansen,S Venkataraman,P Stevenson,Y Yang,L Richardson,N Burton,TP Perry,P Smith,RA Baldock,DR Davidson,JH Christiansen,

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EMAGE Edinburgh Mouse Atlas of Gene Expression: 2008 update. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Nucleic acids research

VOLUME: 36

Page Numbers: D860-5

Journal Abbreviation: Nucleic Acids Res.

ISSN: 1362-4962

DAY: 12

MONTH: 12

YEAR: 2007

EMAGE Edinburgh Mouse Atlas of Gene Expression: 2008 update. Information

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LANGUAGE: eng

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Grant and Affiliation Information for EMAGE Edinburgh Mouse Atlas of Gene Expression: 2008 update.

AFFILIATION: MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.

Country: England

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MEDLINETA: Nucleic Acids Res

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