Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer.

Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer. Research Abstract Details 

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Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer. Abstract Text:

Nimisha Srivastava,Mark A Burns,

We describe three droplet sensing techniques: a digital electrode, an analog electrode, and a thermal method. All three techniques use a single layer of metal lines that is easy to microfabricate and an electronic signal can be produced using low DC voltages. While the electrode methods utilize changes in electrical conductivity when the air/liquid interface of the droplet passes over a pair of electrodes, the thermal method is based on convective heat loss from a locally heated region. For the electrode method, the analog technique is able to detect 25 nL droplets while the digital technique is capable of detecting droplets as small as 100 pL. For thermal sensing, temperature profiles in the range of 36 degrees C and higher were used. Finally, we have used the digital electrode method and an array of electrodes located at preset distances to automate the operation of a previously described microfluidic viscometer. The viscometer is completely controlled by a laptop computer, and the total time for operation including setup, calibration, sample addition and viscosity calculation is approximately 4 minutes.

Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer. Publishing Authors By Initials

N Srivastava,MA Burns,

For similar natural sciences: chemistry: chemistry, physical: viscosity research abstracts see: natural sciences: chemistry: chemistry, physical: viscosity research

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MEDLINE DATE:

Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Lab on a chip

VOLUME: 6

Page Numbers: 744-51

Journal Abbreviation:

ISSN: 1473-0197

DAY: 24

MONTH: 03

YEAR: 2006

Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101128948

Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer. Keywords Mesh Terms:

KEYWORDS: Viscosity

MESH TERMS: chemistry

Chemical & Substance for Abstract: Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer. Information

Substance Name: Silicon

Registry Number: 7440-21-3

Grant and Affiliation Information for Electronic drop sensing in microfluidic devices: automated operation of a nanoliter viscometer.

AFFILIATION: Department of Chemical Engineering, The University of Michigan, Ann Arbor, MI 48109-2136, USA.

Country: England

AGENCY: United States NIAID

GRANT: R21 AI049541-04

ACRONYM: AI

MEDLINETA: Lab Chip

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