Electron cryotomography reveals the portal in the herpesvirus capsid.

Electron cryotomography reveals the portal in the herpesvirus capsid. Research Abstract Details 

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Electron cryotomography reveals the portal in the herpesvirus capsid. Abstract Text:

Juan T Chang,Michael F Schmid,Frazer J Rixon,Wah Chiu,

Herpes simplex virus type 1 is a human pathogen responsible for a range of illnesses from cold sores to encephalitis. The icosahedral capsid has a portal at one fivefold vertex which, by analogy to portal-containing phages, is believed to mediate genome entry and exit. We used electron cryotomography to determine the structure of capsids lacking pentons. The portal vertex appears different from pentons, being located partially inside the capsid shell, a position equivalent to that of bacteriophage portals. Such similarity in portal organization supports the idea of the evolutionary relatedness of these viruses.

Electron cryotomography reveals the portal in the herpesvirus capsid. Publishing Authors By Initials

JT Chang,MF Schmid,FJ Rixon,W Chiu,

For similar organic chemicals: urea research abstracts see: organic chemicals: urea research

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Electron cryotomography reveals the portal in the herpesvirus capsid. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of virology

VOLUME: 81

Page Numbers: 2065-8

Journal Abbreviation: J. Virol.

ISSN: 0022-538X

DAY: 6

MONTH: 12

YEAR: 2006

Electron cryotomography reveals the portal in the herpesvirus capsid. Information

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LANGUAGE: eng

NlmUniqueID: 113724

Electron cryotomography reveals the portal in the herpesvirus capsid. Keywords Mesh Terms:

KEYWORDS: Urea

MESH TERMS: chemistry

Chemical & Substance for Abstract: Electron cryotomography reveals the portal in the herpesvirus capsid. Information

Substance Name: Urea

Registry Number: 57-13-6

Grant and Affiliation Information for Electron cryotomography reveals the portal in the herpesvirus capsid.

AFFILIATION: Graduate Program in Structural and Computational Biology and Molecular Biophysics, National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.

Country: United States

AGENCY: United States NIAID

GRANT: R01AI38469

ACRONYM: AI

MEDLINETA: J Virol

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