Electrochemical polymerization of conducting polymers in living neural tissue.

Electrochemical polymerization of conducting polymers in living neural tissue. Research Abstract Details 

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Electrochemical polymerization of conducting polymers in living neural tissue. Abstract Text:

Sarah M Richardson-Burns,Jeffrey L Hendricks,David C Martin,

A number of biomedical devices require extended electrical communication with surrounding tissue. Significant improvements in device performance would be achieved if it were possible to maintain communication with target cells despite the reactive, insulating scar tissue that forms at the device-tissue interface. Here, we report that the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) can be polymerized directly within living neural tissue resulting in an electrically conductive network that is integrated within the tissue. Nano and microscale PEDOT filaments extend out from electrode sites, presumably forming within extracellular spaces. The cloud of PEDOT filaments penetrates out into the tissue far enough that it should be possible to bypass fibrous scar tissue and contact surrounding healthy neurons. These electrically functional, diffuse conducting polymer networks grown directly within tissue signify a new paradigm for creating soft, low impedance implantable electrodes.

Electrochemical polymerization of conducting polymers in living neural tissue. Publishing Authors By Initials

SM Richardson-Burns,JL Hendricks,DC Martin,

For similar macromolecular substances: polymers research abstracts see: macromolecular substances: polymers research

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Electrochemical polymerization of conducting polymers in living neural tissue. Journal Published:

PUBLICATION TYPE: Review

Journal: Journal of neural engineering

VOLUME: 4

Page Numbers: L6-L13

Journal Abbreviation:

ISSN: 1741-2560

DAY: 2

MONTH: 02

YEAR: 2007

Electrochemical polymerization of conducting polymers in living neural tissue. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101217933

Electrochemical polymerization of conducting polymers in living neural tissue. Keywords Mesh Terms:

KEYWORDS: Polymers

MESH TERMS: radiation effects

Chemical & Substance for Abstract: Electrochemical polymerization of conducting polymers in living neural tissue. Information

Substance Name: poly(3,4-ethylene dioxythiophene)

Registry Number: 0

Grant and Affiliation Information for Electrochemical polymerization of conducting polymers in living neural tissue.

AFFILIATION: Regenerative Sciences Program, University of Michigan, Ann Arbor, MI 48109, USA.

Country: England

AGENCY: United States NIDDK

GRANT: T90-DK070071-02

ACRONYM: DK

MEDLINETA: J Neural Eng

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