Electroacupuncture alters the expression of genes associated with lipid metabolism and immune reaction in liver of hypercholesterolemia mice.

Electroacupuncture alters the expression of genes associated with lipid metabolism and immune reaction in liver of hypercholesterolemia mice. Research Abstract Details 

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Electroacupuncture alters the expression of genes associated with lipid metabolism and immune reaction in liver of hypercholesterolemia mice. Abstract Text:

Yaoxia Kang,Min Li,Wenqi Yan,Xingjie Li,Jinmei Kang,Yizheng Zhang,Yaoxia Kang,Min Li,Wenqi Yan,Xingjie Li,Jinmei Kang,Yizheng Zhang,Yaoxia Kang,Min Li,Wenqi Yan,Xingjie Li,Jinmei Kang,Yizheng Zhang,

Acupuncture or electroacupuncture (EA) is effective in treating various metabolism disorders. Previously we found that EA at the acupoint, Fenglong (ST40), had the cholesterol-lowering effect and regulated genes expression in liver of hypercholesterolemia mice (M Li and YZ Zhang, Int J Mol Med 2007, 19: 617-629). To explain gene expression associated with EA, suppression subtractive hybridization (SSH), combined with targeted display (TD), was used and 26 up-regulated and 24 down-regulated genes with known functions were identified in hypercholesterolemia mice liver, some of which are involved in key reactions of lipid metabolism and immune reaction. Promoting lipid metabolism and suppressing inflammation via modulating mRNA expression may be the mechanism of EA inducing modulation of cholesterol concentrations.

Electroacupuncture alters the expression of genes associated with lipid metabolism and immune reaction in liver of hypercholesterolemia mice. Publishing Authors By Initials

Y Kang,M Li,W Yan,X Li,J Kang,Y Zhang,Y Kang,M Li,W Yan,X Li,J Kang,Y Zhang,Y Kang,M Li,W Yan,X Li,J Kang,Y Zhang,

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Electroacupuncture alters the expression of genes associated with lipid metabolism and immune reaction in liver of hypercholesterolemia mice. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Biotechnology letters

VOLUME: 29

Page Numbers: 1817-24

Journal Abbreviation: Biotechnol. Lett.

ISSN: 0141-5492

DAY: 18

MONTH: 08

YEAR: 2007

Electroacupuncture alters the expression of genes associated with lipid metabolism and immune reaction in liver of hypercholesterolemia mice. Information

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LANGUAGE: eng

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AFFILIATION: College of Life Science, Sichuan University, Chengdu, Sichuan, 610064, P.R. China, yizzhang@scu.edu.cn.

Country: Netherlands

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MEDLINETA: Biotechnol Lett

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