Efficiency of ultralow doses of antibodies to s100 protein and delta sleep-inducing Peptide in rats with anxious depression.

Efficiency of ultralow doses of antibodies to s100 protein and delta sleep-inducing Peptide in rats with anxious depression. Research Abstract Details 

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Efficiency of ultralow doses of antibodies to s100 protein and delta sleep-inducing Peptide in rats with anxious depression. Abstract Text:

L V Loskutova,M B Shtark,O I Epstein,

We studied the effects of single peroral treatment with antibodies against S100 protein and delta sleep-inducing peptide in ultralow doses on behavioral characteristics of rats with anxious depression produced by acute stress (unavoidable electrical shock). Stress-produced behavioral changes and anxiolytic activity of antibodies were determined using the elevated plus-maze, open field, and tail suspension tests. High efficiency of the mixture of antibodies against S100 protein and delta sleep-inducing peptide was observed in all tests. Anxiolytic activity of anti-S100 antibodies (although less pronounced than that of the mixture of antibodies) was revealed in the elevated plus-maze and tail suspension test.

Efficiency of ultralow doses of antibodies to s100 protein and delta sleep-inducing Peptide in rats with anxious depression. Publishing Authors By Initials

LV Loskutova,MB Shtark,OI Epstein,

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Efficiency of ultralow doses of antibodies to s100 protein and delta sleep-inducing Peptide in rats with anxious depression. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Bulletin of experimental biology and medicine

VOLUME: 135 Suppl 1

Page Numbers: 20-2

Journal Abbreviation: Bull. Exp. Biol. Med.

ISSN: 0007-4888

DAY: 1

MONTH: 09

YEAR: 2003

Efficiency of ultralow doses of antibodies to s100 protein and delta sleep-inducing Peptide in rats with anxious depression. Information

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LANGUAGE: eng

NlmUniqueID: 372557

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Grant and Affiliation Information for Efficiency of ultralow doses of antibodies to s100 protein and delta sleep-inducing Peptide in rats with anxious depression.

AFFILIATION: Institute of Molecular Biology and Biophysics, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk; "Materia Medica Holding" Research-and-Production Company, Moscow.

Country: United States

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MEDLINETA: Bull Exp Biol Med

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