[Efficacy of trastuzumab alone therapy was compared to trastuzumab plus taxane therapy in patients of advanced and metastatic breast cancers]

[Efficacy of trastuzumab alone therapy was compared to trastuzumab plus taxane therapy in patients of advanced and metastatic breast cancers] Research Abstract Details 

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[Efficacy of trastuzumab alone therapy was compared to trastuzumab plus taxane therapy in patients of advanced and metastatic breast cancers] Abstract Text:

Kenichi Sakurai,Katsuhisa Enomoto,Akira Kitajima,Mayumi Tani,Sadao Amano,Kenichi Sakurai,Katsuhisa Enomoto,Akira Kitajima,Mayumi Tani,Sadao Amano,

We compared trastuzumab alone therapy (A-group) (n=6) to trastuzumab plus taxane therapy (B-group) (n=12) in patients of advanced and metastatic breast cancers. The response rate of A-group was 33.3%. Six months after, A-group was switched to trastuzumab plus taxane therapy. The response rate of A-group after addition of taxane was improved to 83.3%. The mean duration of response was 6.8 months in A-group after addition of taxane. The response rate of B-group was 83.3%. The mean duration of response was 7.5 months in B-group. The combination therapy of trastuzumab and taxane therapy showed a high response rate. We think that it is possible to start trastuzumab alone therapy because A-group after addition of taxane showed a high response rate. There were no significant differences of immunosuppressive acidic protein (IAP) from the course of chemotherapy in all cases.

[Efficacy of trastuzumab alone therapy was compared to trastuzumab plus taxane therapy in patients of advanced and metastatic breast cancers] Publishing Authors By Initials

K Sakurai,K Enomoto,A Kitajima,M Tani,S Amano,K Sakurai,K Enomoto,A Kitajima,M Tani,S Amano,

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[Efficacy of trastuzumab alone therapy was compared to trastuzumab plus taxane therapy in patients of advanced and metastatic breast cancers] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Gan to kagaku ryoho. Cancer & chemotherapy

VOLUME: 34

Page Numbers: 1911-3

Journal Abbreviation: Gan To Kagaku Ryoho

ISSN: 0385-0684

DAY: 28

MONTH: Nov

YEAR: 2007

[Efficacy of trastuzumab alone therapy was compared to trastuzumab plus taxane therapy in patients of advanced and metastatic breast cancers] Information

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LANGUAGE: jpn

NlmUniqueID: 7810034

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Grant and Affiliation Information for [Efficacy of trastuzumab alone therapy was compared to trastuzumab plus taxane therapy in patients of advanced and metastatic breast cancers]

AFFILIATION: Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.

Country: Japan

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MEDLINETA: Gan To Kagaku Ryoho

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