[Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases]

[Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases] Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

[Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases] Abstract Text:

Zhong-Jun Xia,Feng-Hua Wang,Hui-Qiang Huang,Hui-Yan Luo,Yu-Hong Li,Tong-Yu Lin,Wen-Qi Jiang,Zhong-Zhen Guan,

BACKGROUND & OBJECTIVE: The efficacy of rituximab given alone or in combination with chemotherapy on naive or relapsed indolent lymphoma is good. This study was to investigate the efficacy and safety of rituximab-containing regimens for patients with indolent B-cell lymphoma in China. METHODS: From Mar. 1999 to Jan. 2005, 34 patients with indolent B-cell lymphoma received rituximab-containing regimens with a median of 5 cycles (ranged from 3 to 8 cycles). Of the 34 patients, 2 received rituximab alone, and 32 received rituximab-based regimens, which including CHOP (16 cases), FMD (5 cases), CHOPE (4 cases), EPOCH (2 cases), DICE (2 cases), DAHP (2 cases), and FN (1 case). RESULTS: Of the 34 patients, 30 were evaluable for objective response. The overall response (OR) rate was 93.3%, and the complete response (CR) rate was 60.0%; the OR rate and CR rate of 22 evaluable naive patients were 95.4% and 66.7%, those of 18 evaluable follicular lymphoma patients were 88.9% and 66.7%. With a median follow-up of 17 months (4-68 months), the 1-year progression-freely survival rate was 85.3%. Myelosuppression was the major adverse event: 19 patients suffered from leukopenia with 4 cases of grade III-IV event, 5 suffered from thrombocytopenia with 4 cases of grade III-IV event, and 2 suffered from febrile neutropenia. Other adverse events included grade I-II nausea/vomiting, mild alopecia, and transient liver function abnormality. The infusional reaction of rituximab consisted of grade I-II rigor/febrile, skin rash, mild hypotension, and asymptomatic ventricular premature beat. CONCLUSION: Rituximab-containing chemotherapeutic regimens are effective for indolent B-cell lymphoma with mild toxicity.

[Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases] Publishing Authors By Initials

ZJ Xia,FH Wang,HQ Huang,HY Luo,YH Li,TY Lin,WQ Jiang,ZZ Guan,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

[Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Ai zheng = Aizheng = Chinese journal of cancer

VOLUME: 25

Page Numbers: 490-4

Journal Abbreviation: Ai Zheng

ISSN: 1000-467X

DAY: 14

MONTH: Apr

YEAR: 2006

[Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases] Information

Number of References:

LANGUAGE: chi

NlmUniqueID: 9424852

[Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases] Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: [Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases] Information

Substance Name:

Registry Number:

Grant and Affiliation Information for [Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases]

AFFILIATION: State Key Laboratory of Oncology in South China, Guangzhou, Guangdong 510060, P. R. China. xiazhj@medmail.com.cn

Country: China

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Ai Zheng

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases Related Publications

• A convergent synthesis of new beta-turn mimics by click chemistry.
• Cell biology. Integrins, rafts, Rac, and Rho.
• Effect of electroacupuncture on reperfusion ventricular arrhythmia in rat.
• Function of the Rho family GTPases in Ras-stimulated Raf activation.
• Measurements of TSC2 GAP Activity Toward Rheb.
• Spatial self-organization in a cyclic resource-species model.
• The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding.
• Variants in mitochondrial tRNAGlu, tRNAArg, and tRNAThr may influence the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in three Han Chinese families with hearing loss.
• [Association of tumor necrosis factors-beta gene polymorphism with endometriosis in women in Guangdong Province]
• [Cloning and expression analysis of lung carcinoma related gene HLCDG1]
• [Determination of germanium in A. arborescens by spectrophotometric method]
• [Determination of organophosphorous pesticide residues in red wine by solid phase microextraction-gas chromatography]
• [Determination of partition coefficient of dissolved gases in transformer oil using phase ratio variation method and static headspace gas chromatography]
• [Diagnosis and treatment for the neck lump caused by migrating foreign body from the pharynx]
• [Effects of 2A-1-1 on the aggregation and Ca2+ influx of platelets.]
• [Effects of caspase-3 inhibitor on the neuronal apoptosis in rat cerebral cortex after ischemia-reperfusion injury]
• [Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases]
• [Efficacy of rituximab-containing salvage regimens on relapsed or refractory B-cell non-Hodgkin's lymphoma]
• [Expression of cellular adhesion molecules and HLA-DR antigen on vascular endothelial cells in hemangiomas.]
• [Influence of free radical inducer on the level of oxidative stress in brain of rats with fluorosis]
• [Lecture of principles and applications of capillary electrophoresis (V) Applications of capillary electrophoresis in pharmaceutical analysis and clinical chemistry]
• [Liver X receptors mediate cholesterol efflux in mouse glomerular mesangial cells]
• [Phase I clinical trial of intravenous recombinant human lymphotoxin-alpha derivative]
• [Preliminary study on planar two-dimensional capillary electrophoresis]
• [Primary central nervous system lymphoma--a report of 32 cases with literature review]
• [Progress in the study of angiopoietin-like protein 3]
• [Rat bone mesenchymal stem cells in vitro differentiation into neuron-like cells induced by Salvis miltorrhiza for injection]
• [Risk factors for nosocomial infections after total knee replacement]
• [Study of rare earth bifunctional chelate BCPDA-Eu3+ labeling protein]
• [Three-dimensional conformal radiation therapy for malignant tumors (report of 1,024 cases)]