Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases.

Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases. Research Abstract Details 

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Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases. Abstract Text:

Anne M Chapas,Kimberly Eickhorst,Roy G Geronemus,Anne M Chapas,Kimberly Eickhorst,Roy G Geronemus,

BACKGROUND: Port wine stains (PWS) affect 0.3-0.5% of both sexes of newborns, usually occurring on the face. OBJECTIVE: To document safety and effectiveness of cryogen spray cooled, pulsed-dye laser at higher fluences than previously used to lighten facial PWS in infants < or =6 months, and establish that frequent treatment early in life yields better clearance than if delayed until later in life. MATERIALS AND METHODS: Forty-nine infants who had been treated with pulsed-dye laser treatments for facial PWS at < or =6 months were identified by case review of photographs, age, sex, PWS severity score prior to laser treatment, number of treatments, and improvement following laser therapy. RESULTS: Patients averaged 9.3 (range 2-16) treatments at 4-6 week intervals at 7.75-9.5 J/cm(2). Average surface area treated was 24.0% with 88.6% average clearance after 1 year. Average clearance was 90.7% for lesions covering <20% surface area and 85.6% for lesions > or =20%. Location (V1, V2, V3, eye, and/or scalp), treated surface area, treatment number, and fluence predicted clearance. Average clearance for sole involvement of V1 was highest (at 93.8%), followed by V2 (at 91.1%), V3 (at 84.3%), V1/V2 (at 83.7%), V1/V2/V3 (at 81.0%), periocular (at 88.6%), and scalp (at 89.9%). All patients tolerated the higher treatment fluences without atrophy or scarring. DISCUSSION/CONCLUSIONS: Frequent, high energy pulsed-dye laser treatments are safe and highly effective in improving facial PWS in infants < or =6 months of age. Patients with PWS should be referred for pulsed-dye laser treatment during early infancy.

Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases. Publishing Authors By Initials

AM Chapas,K Eickhorst,RG Geronemus,AM Chapas,K Eickhorst,RG Geronemus,

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Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Lasers in surgery and medicine

VOLUME: 39

Page Numbers: 563-8

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ISSN: 0196-8092

DAY: 26

MONTH: Aug

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: Laser & Skin Surgery Center of New York, New York, NY, 10016, USA. achapas@laserskinsurgery.com

Country: United States

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MEDLINETA: Lasers Surg Med

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