Effects of zeranol upon bovine testicular function.

Effects of zeranol upon bovine testicular function. Research Abstract Details 

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Effects of zeranol upon bovine testicular function. Abstract Text:

P E Juniewicz,T H Welsh,B H Johnson,

Effects of zeranol upon testicular function in bulls were studied. In Experiment I, young bulls (104+/-1.7 days of age) were either implanted with 36 mg zeranol or served as controls with reimplantation on days 56 and 112 after first implant. After a 168-day treatment period, half the bulls were orchidectomized with the remaining bulls assigned to a 168-day recovery period, after which they were also orchidectomized. Zeranol inhibited testicular development during the treatment period. Testosterone (T) concentrations were lower (P<0.01) in treated bulls. Spermatozoa were absent in testes of treated bulls while control bulls averaged 27x10(6) sperm per gram of testis. At the end of the 168-day recovery period, testes weights and sperm concentrations were similar (P>0.10) between bulls previously treated with zeranol and controls. Implantation of older bulls with either 36 mg (267+/-3.4 days of age: Experiment II) or 72 mg (16 months of age: Experiment III) of zeranol had no effect (P>0.10) upon spermatogenesis or T production over a 168-day treatment period. The results indicate that the inhibitory effects of zeranol upon bovine testicular function are age-dependent and suggest that there may be an increased sensitivity of the hypothalmic-pituitary-testicular axis to zeranol in the prepuberal bull.

Effects of zeranol upon bovine testicular function. Publishing Authors By Initials

PE Juniewicz,TH Welsh,BH Johnson,

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Effects of zeranol upon bovine testicular function. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Theriogenology

VOLUME: 23

Page Numbers: 565-82

Journal Abbreviation: Theriogenology

ISSN: 0093-691X

DAY: 26

MONTH: Apr

YEAR: 1985

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LANGUAGE: eng

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AFFILIATION: Reproductive Physiology Research Laboratory Department of Animal Science North Carolina State University Raleigh, North Carolina 27695-7621 USA.

Country: United States

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MEDLINETA: Theriogenology

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