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Effects of urogastrone (epidermal growth factor) on the intestinal epithelium.

Effects of urogastrone (epidermal growth factor) on the intestinal epithelium. Research Abstract Details 

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  • Effects of urogastrone (epidermal growth factor) on the intestinal epithelium. Abstract Text:

    r a goodladR A Goodlad,t j wilsonT J Wilson,w lentonW Lenton,h gregoryH Gregory,k g mccullaghK G McCullagh,n a wrightN A Wright,

    Recombinant urogastrone (human epidermal growth factor) was infused into rats in which intestinal cell proliferation was reduced to a steady state basal level by feeding them intravenously. Urogastrone elevated the augmented metaphase index and weight of all sections of the gastrointestinal tract in a dose-related manner. Infusion of urogastrone at a dose which has a minimal effect on gastric acid secretion significantly increased crypt cell production and tissue weights throughout the gastrointestinal tract. Intravenous urogastrone was also effective in restoring cell proliferation after the intestine had become hypoproliferative. Urogastrone administered luminally had no significant effect on either intestinal weight, crypt cell production rate, or metaphase collection.

    Effects of urogastrone (epidermal growth factor) on the intestinal epithelium. Publishing Authors By Initials

    ra goodladRA Goodlad,tj wilsonTJ Wilson,w lentonW Lenton,h gregoryH Gregory,kg mccullaghKG McCullagh,na wrightNA Wright,

    For similar proteins: recombinant proteins research abstracts see: proteins: recombinant proteins research

    PUBMED ID PMID:

    MEDLINE DATE:

    Effects of urogastrone (epidermal growth factor) on the intestinal epithelium. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Zeitschrift für Gastroenterologie. Verhandlungsban

    VOLUME: 23

    Page Numbers: 171-7

    Journal Abbreviation:

    ISSN: 0172-8504

    DAY: 12

    MONTH: Apr

    YEAR: 1988

    Effects of urogastrone (epidermal growth factor) on the intestinal epithelium. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 1256344

    Effects of urogastrone (epidermal growth factor) on the intestinal epithelium. Keywords Mesh Terms:

    KEYWORDS: Recombinant Proteins

    MESH TERMS: pharmacology

    Chemical & Substance for Abstract: Effects of urogastrone (epidermal growth factor) on the intestinal epithelium. Information

    Substance Name: Epidermal Growth Factor

    Registry Number: 62229-50-9

    Grant and Affiliation Information for Effects of urogastrone (epidermal growth factor) on the intestinal epithelium.

    AFFILIATION:

    Country: GERMANY, WEST

    GERMANY, WEST Research PublicationGERMANY, WEST Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Z Gastroenterol Verh

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

    Effects of urogastrone epidermal growth factor on the intestinal epithelium Related Publications

     

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