Effects of testosterone and 5alpha-dihydrotestosterone on luteal lifespan in dairy heifers.

Effects of testosterone and 5alpha-dihydrotestosterone on luteal lifespan in dairy heifers. Research Abstract Details 

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Effects of testosterone and 5alpha-dihydrotestosterone on luteal lifespan in dairy heifers. Abstract Text:

W J Silvia,A L Jacobs,S H Hayes,

Endogenous concentrations of testosterone increase approximately 7 d prior to estrus in cattle and goats. Inhibition of testosterone synthesis results in a delay of luteal regression in both species. The purpose of this experiment was to determine if treatment with testosterone or 5alpha-dihydrotestosterone (DHT), 2 to 6 d prior to the endogenous rise in testosterone, would result in premature luteal regression. Sixteen heifers were randomly assigned to one of three treatment groups: 1) Control (n = 6); 2) testosterone (100 mug, n = 5); or 3) DHT (100 mug, n = 5). Each heifer received a single injection of the appropriate steriod on Day 8, 9, 10, 11 or 12 post estrus. Jugular venous blood samples were collected at frequent intervals for 24 h to quantify testosterone, and then daily for 14 d to quantify progesterone. Concentrations of testosterone increased within 15 min of injection of testosterone, and reached a maximum at 30 min. Concentrations were maintained at > 2 ng/ml throughout the first 24 h after injection. Based on concentrations of progesterone, neither androgen had any effect on the lifespan of the corpus luteum or the level of luteal function.

Effects of testosterone and 5alpha-dihydrotestosterone on luteal lifespan in dairy heifers. Publishing Authors By Initials

WJ Silvia,AL Jacobs,SH Hayes,

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Effects of testosterone and 5alpha-dihydrotestosterone on luteal lifespan in dairy heifers. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Theriogenology

VOLUME: 32

Page Numbers: 871-6

Journal Abbreviation: Theriogenology

ISSN: 0093-691X

DAY: 26

MONTH: Nov

YEAR: 1989

Effects of testosterone and 5alpha-dihydrotestosterone on luteal lifespan in dairy heifers. Information

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LANGUAGE: eng

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AFFILIATION: Dept of Animal Sciences University of Kentucky, Lexington, KY 40546-0215 USA.

Country: United States

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MEDLINETA: Theriogenology

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