[Effects of Rg1 on calcium channel of guinea pig ventricular myocytes]

[Effects of Rg1 on calcium channel of guinea pig ventricular myocytes] Research Abstract Details 

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[Effects of Rg1 on calcium channel of guinea pig ventricular myocytes] Abstract Text:

B Zhang,S Jin,X Kuang,W Yao,G Xia,M Jiang,

OBJECTIVE: To evaluate the effect of Rg1 (purified saponin of Panax notoginseng) on L-Ca2+ channel of guinea pig ventricular myocytes. METHOD: The whole-cell patch clamp recording technique. RESULT: When the holding potential was kept at -40 mV, and the cell was depolarized to +40 mV for 150 ms at a frequency of 0.5 Hz.Rg1 10 mumol.L-1 and 30 mumol.L-1 could not reduce Bay K 8644 and nifedipine-sensitive L-type Ca2+ inward current (P > 0.05, n = 5). CONCLUSION: Rg1 should not be a Ca2+ channel antagonist.

[Effects of Rg1 on calcium channel of guinea pig ventricular myocytes] Publishing Authors By Initials

B Zhang,S Jin,X Kuang,W Yao,G Xia,M Jiang,

For similar plants: plants, medicinal research abstracts see: plants: plants, medicinal research

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[Effects of Rg1 on calcium channel of guinea pig ventricular myocytes] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazh

VOLUME: 24

Page Numbers: 624-6, 640

Journal Abbreviation: Zhongguo Zhong Yao Za Zhi

ISSN: 1001-5302

DAY: 6

MONTH: Oct

YEAR: 1999

[Effects of Rg1 on calcium channel of guinea pig ventricular myocytes] Information

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LANGUAGE: chi

NlmUniqueID: 8913656

[Effects of Rg1 on calcium channel of guinea pig ventricular myocytes] Keywords Mesh Terms:

KEYWORDS: Plants, Medicinal

MESH TERMS: chemistry

Chemical & Substance for Abstract: [Effects of Rg1 on calcium channel of guinea pig ventricular myocytes] Information

Substance Name: Ginsenosides

Registry Number: 0

Grant and Affiliation Information for [Effects of Rg1 on calcium channel of guinea pig ventricular myocytes]

AFFILIATION: ICU, Hospital of Chinese Traditional Medicine of Guangdong Province, Fu Shan 528000.

Country: China

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MEDLINETA: Zhongguo Zhong Yao Za Zhi

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