Effects of milk supplementation on cortical bone gain in Chinese girls aged 10-12 years.

Effects of milk supplementation on cortical bone gain in Chinese girls aged 10-12 years. Research Abstract Details 

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Effects of milk supplementation on cortical bone gain in Chinese girls aged 10-12 years. Abstract Text:

K Zhu,H Greenfield,X Du,Q Zhang,D R Fraser,

Objective - To study the effect of milk supplementation on cortical bone gain in Chinese girls aged 10-12 years. Design - a 24 months double-blind, controlled supplementation trial with vitamin D and/or calcium fortified milk in 757 Beijing girls aged 10 years. Subjects were randomized into three groups according to their schools, with 238 girls in Milk + Ca group receiving 330 ml calcium fortified UHT milk per school day, 260 girls in Milk + Ca + Vit D group receiving 330 ml calcium and vitamin D fortified UHT milk per school day, and 259 unsupplemented girls in the control group. X-ray radiographs of the non-dominant hand were obtained in 606 girls (177, 210, 219 from Milk + Ca, Milk + Ca + Vit D and control groups, respectively) at baseline and 24 months. Periosteal diameter (outer width) and medullary diameter (inner width) of the midshaft of the second metacarpal were measured with a digital caliper (Mitutoyo, Japan). The combined cortical thickness (CCT) was calculated as: outer width - inner width. Outcomes - After 24 months, in comparison with controls, both supplemented groups had significantly higher percentage gains in periosteal diameter (8.95 +/- 0.24, 9.32 +/- 0.24 vs 8.14 +/- 0.19, P =0.036 and P<0.001, respectively), lower gains in medullary diameter (-3.23 +/- 1.06, -1.14 +/- 0.86 vs 4.51 +/- 1.03, P<0.001), and higher gains in CCT (20.75 +/- 1.08, 19.45 +/- 0.94 vs 12.58 +/- 0.97, P<0.001). Conclusions - Milk supplementation (330ml with a total of 560mg calcium with/without 8microg vitamin D on school days over 24 months) led to greater periosteal apposition and cortical bone gain in Chinese adolescent girls, thus conferring greater bone strength on the supplemented girls.

Effects of milk supplementation on cortical bone gain in Chinese girls aged 10-12 years. Publishing Authors By Initials

K Zhu,H Greenfield,X Du,Q Zhang,DR Fraser,

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Effects of milk supplementation on cortical bone gain in Chinese girls aged 10-12 years. Journal Published:

PUBLICATION TYPE: Randomized Controlled Trial

Journal: Asia Pacific journal of clinical nutrition

VOLUME: 12 Suppl

Page Numbers: S47

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ISSN: 0964-7058

DAY: 16

MONTH: 03

YEAR: 2003

Effects of milk supplementation on cortical bone gain in Chinese girls aged 10-12 years. Information

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LANGUAGE: eng

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AFFILIATION: Faculty of Veterinary Science, University of Sydney, NSW 2006.

Country: Australia

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MEDLINETA: Asia Pac J Clin Nutr

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