Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle.

Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle. Research Abstract Details 

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Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle. Abstract Text:

T Mayahara,K Suzuki,H Ohata,T Kamimura,

Myosin B was extracted from rabbit fast skeletal muscle. Caffeine (2-70 mM), theophylline (2-30 mM), and theobromine (2 mM) were examined for their effects on the rate and extent of myosin B superprecipitation at a low ionic strength (50 mM KCl) and a low concentration of ATP (40 microM) by the turbidimetric method. The rate of the superprecipitation was significantly (p less than 0.05 and p less than 0.01) reduced by 30-70 mM caffeine and 2-30 mM theophylline, while the extent was significantly (p less than 0.01) increased by 10-30 mM theophylline. The onset of the superprecipitation was also delayed and a clearing phase was even induced by 50-70 mM caffeine. Theobromine had no significant effect on the rate or extent of the superprecipitation at the concentration used. These results indicate that caffeine and theophylline are retardants of the myosin B superprecipitation reaction in the concentration ranges investigated.

Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle. Publishing Authors By Initials

T Mayahara,K Suzuki,H Ohata,T Kamimura,

For similar heterocyclic compounds: alkaloids: xanthines research abstracts see: heterocyclic compounds: alkaloids: xanthines research

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Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 91

Page Numbers: 651-5

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Feb

YEAR: 1982

Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle. Keywords Mesh Terms:

KEYWORDS: Xanthines

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle. Information

Substance Name: Myosins

Registry Number: EC 3.6.1.4

Grant and Affiliation Information for Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle.

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Country: JAPAN

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MEDLINETA: J Biochem

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