[Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block]

[Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block] Research Abstract Details 

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[Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block] Abstract Text:

Shi-Wei Liang,Chun-Shui Lin,Jin-Fang Xiao,Miao-Ning Gu,

OBJECTIVE: To investigate the effects of intraperitoneal CO2 insufflation on the hemodynamics, oxygen consumption (VO2) and carbon dioxide production (VCO2) during intravenous anesthesia with propofol in combination with epidural block. METHODS: Intratracheal intubation was performed after rapid induction of anesthesia and mechanical ventilation was given. Maintenance of anesthesia was achieved using continuous intravenous propofol infusion (2 mg/kg/h) ?N2O inhalation and intermittent epidural administration. Indices of hemodynamics and respiratory function were collected 5 min before induction, 1 min before CO2 insufflation, and 5, 10, 20, 30, 40, 50, 60 min after the start of insufflation and 5 min after the termination of insufflation. RESULTS: The mean arterial pressure (MAP), heart rate (HR), end-tidal PCO2 (P(ET)CO2), VO2 and VCO2 1 min before insufflation were markedly reduced(P<0.01), compared with those recorded before induction. MAP and HR did not undergo any conspicuous changes during CO2 insufflation and 5 min after insufflation termination. Compared with that 1 min before insufflation, PETCO2 was significantly increased 20 min after the start of insufflation (P<0.01), and subsequently carried on the increase though of a lesser scale. VO2 and VCO2 gradually rose after the start of insufflation, and VO2 presented a significantly elevation (P<0.01) 10 min after the insufflation while VCO2 did not show this marked increase(P<0.05) till 20 min after the insufflation in comparison with the levels before insufflation. Subsequently, VO2 continued to rise and VCO2 also retained the increase but of smaller magnitude. CONCLUSION: Intravenous propofol anesthesia combined with epidural block assisted by well-managed excessive ventilation before insufflation can alleviate the adverse effects of CO2 insufflation on respiratory and circulatory systems.

[Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block] Publishing Authors By Initials

SW Liang,CS Lin,JF Xiao,MN Gu,

For similar organic chemicals: phenols: propofol research abstracts see: organic chemicals: phenols: propofol research

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[Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Di 1 jun yi da xue xue bao = Academic journal of t

VOLUME: 22

Page Numbers: 166-7

Journal Abbreviation: Di Yi Jun Yi Da Xue Xue Bao

ISSN: 1000-2588

DAY: 25

MONTH: Feb

YEAR: 2002

[Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block] Information

Number of References:

LANGUAGE: chi

NlmUniqueID: 9426110

[Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block] Keywords Mesh Terms:

KEYWORDS: Propofol

MESH TERMS: drug effects

Chemical & Substance for Abstract: [Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block] Information

Substance Name: Propofol

Registry Number: 2078-54-8

Grant and Affiliation Information for [Effects of intraperitoneal CO2 insufflation on hemodynamics and oxygen consumption during intravenous propofol anesthesia combined with epidural block]

AFFILIATION: Department of Anesthesiology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.

Country: China

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MEDLINETA: Di Yi Jun Yi Da Xue Xue Bao

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