Effects of highly active antiretroviral therapy on HIV-1-associated oral complications.

Effects of highly active antiretroviral therapy on HIV-1-associated oral complications. Research Abstract Details 

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Effects of highly active antiretroviral therapy on HIV-1-associated oral complications. Abstract Text:

Zahida Parveen,Edward Acheampong,Roger J Pomerantz,Jeffrey M Jacobson,Brian Wigdahl,Muhammad Mukhtar,

The oral cavity of human immunodeficiency virus type I (HIV-1) infected individuals is subjected to a series of opportunistic infections which are usually considered as a prognostic marker for the severity of infection as well as an indicator of immunodeficiency. The highly active antiretroviral therapy (HAART) has significantly lessened the severity of HIV-associated oral infections although this therapeutic regimen is considered to be responsible for some of the oral lesions such as oral warts and salivary gland disorders. In addition, the beneficial effects of HAART on HIV associated oral lesions are stratified with age, with the adult population showing improvements whereas the oral lesions among children remain unchanged with this therapy. The presence of HIV-1 in the saliva, and infectivity of oral epithelial cells suggest that the oral cavity is a site of HIV pathogenesis and potential reservoir for the disease in the setting of virally suppressive HAART. Overall HIV associated oral lesions are usually due to fungal, bacterial, and viral infections as well as some of unknown etiology. This review describes the current status of HIV associated oral lesions by comparing historically available pre-HAART data. Future directions envisioned by the National Institutes of Health as well as novel avenues to be explored are also presented.

Effects of highly active antiretroviral therapy on HIV-1-associated oral complications. Publishing Authors By Initials

Z Parveen,E Acheampong,RJ Pomerantz,JM Jacobson,B Wigdahl,M Mukhtar,

For similar stomatognathic diseases: mouth diseases research abstracts see: stomatognathic diseases: mouth diseases research

PUBMED ID PMID:

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Effects of highly active antiretroviral therapy on HIV-1-associated oral complications. Journal Published:

PUBLICATION TYPE: Review

Journal: Current HIV research

VOLUME: 5

Page Numbers: 281-92

Journal Abbreviation: Curr. HIV Res.

ISSN: 1873-4251

DAY: 3

MONTH: May

YEAR: 2007

Effects of highly active antiretroviral therapy on HIV-1-associated oral complications. Information

Number of References: 182

LANGUAGE: eng

NlmUniqueID: 101156990

Effects of highly active antiretroviral therapy on HIV-1-associated oral complications. Keywords Mesh Terms:

KEYWORDS: Mouth Diseases

MESH TERMS: etiology

Chemical & Substance for Abstract: Effects of highly active antiretroviral therapy on HIV-1-associated oral complications. Information

Substance Name: Anti-HIV Agents

Registry Number: 0

Grant and Affiliation Information for Effects of highly active antiretroviral therapy on HIV-1-associated oral complications.

AFFILIATION: Division of Infectious Diseases, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

Country: Netherlands

AGENCY: United States NICHD

GRANT: HD048958

ACRONYM: HD

MEDLINETA: Curr HIV Res

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