Effects of Exogenous Polyamines on Tropane Alkaloid Production by a Root Culture of Duboisia myoporoides.

Effects of Exogenous Polyamines on Tropane Alkaloid Production by a Root Culture of Duboisia myoporoides. Research Abstract Details 

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Effects of Exogenous Polyamines on Tropane Alkaloid Production by a Root Culture of Duboisia myoporoides. Abstract Text:

T Yoshioka,H Yamagata,A Ithoh,H Deno,Y Fujita,Y Yamada,

The addition of putrescine, a precursor of tropane alkaloids, to the culture medium increased scopolamine production of DUBOISIA MYOPOROIDES R. Br. (Solanaceae) roots (RB-1), whereas, other precursors (ornithine, arginine, and tropine) increased the content of scopolamine only slightly or not at all. Spermidine, a natural polyamine and a direct metabolite of putrescine, increased the scopolamine content of the cultured roots to the same degree as putrescine increased it. High scopolamine root contents were obtained in media supplemented with 3 mM putrescine (0.96%) and 3 mM spermidine (0.94%), whereas spermine decreased scopolamine production. The putrescine analogues diaminomethane, diaminoethane, diaminopropane, and cadaverine also increased the scopolamine content of the DUBOISIA root culture from 0.56% to the respective values of 0.86%, 0.90%, 1.06%, and 1.04%. Other diamines with long alkyl chains and agmatine did not increase scopolamine production.

Effects of Exogenous Polyamines on Tropane Alkaloid Production by a Root Culture of Duboisia myoporoides. Publishing Authors By Initials

T Yoshioka,H Yamagata,A Ithoh,H Deno,Y Fujita,Y Yamada,

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Effects of Exogenous Polyamines on Tropane Alkaloid Production by a Root Culture of Duboisia myoporoides. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Planta medica

VOLUME: 55

Page Numbers: 523-4

Journal Abbreviation: Planta Med.

ISSN: 0032-0943

DAY: 30

MONTH: Dec

YEAR: 1989

Effects of Exogenous Polyamines on Tropane Alkaloid Production by a Root Culture of Duboisia myoporoides. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Effects of Exogenous Polyamines on Tropane Alkaloid Production by a Root Culture of Duboisia myoporoides.

AFFILIATION: Bioscience Research Laboratories, Mitsui Petrochemical Industries, Ltd., 6-1-2 Waki-cho, Kuga-gun, Yamaguchi-ken, 740, Japan.

Country: Germany

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MEDLINETA: Planta Med

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