[Effects of dermal template on the biological behaviors of fibroblasts during wound healing]

[Effects of dermal template on the biological behaviors of fibroblasts during wound healing] Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

[Effects of dermal template on the biological behaviors of fibroblasts during wound healing] Abstract Text:

Yingkai Liu,Shuliang Lu,Chun Qing,Zhenjiang Liao,Jixiang Shi,

OBJECTIVE: To study the effects of dermal template on the biological behaviors of fibroblasts during wound healing. METHODS: A total of 120 rats were made full-thickness wound modes on the dorsum and divided into 4 groups, in group 1, the wounds were allowed to heal by contraction(ConT); in group2, the wounds covered with full-thickness skin grafts (FTSG); in group 3, the wounds were with split thickness skin grafts (STSG); and in group 4, the wounds were covered by dermal regeneration template with overlying thin split-thickness autograft (ADMT). The specimens were obtained at one week, two weeks, four weeks, six weeks, and twelve weeks respectively. The expressions of alpha smooth muscle actin(alpha-SMA, characteristic of MFB), fibronectin (FN), integrin alpha2,beta1 and transforming growth factor beta1 (TGF-beta1) were examined by immunohistochemical analysis. RESULTS: Positive expression of alpha-SMA, FN, integrin alpha2beta1 and TGF-beta1 in ADMT groups was significantly lower than that in STSG group and ConT group, but higher than that in FTSG group (P < 0.05). CONCLUSION: Dermal regeneration template can inhibit the transformation of FB to MFB and restrain the expression of FN, integrin alpha2,beta1, and TGF-beta1 in fibroblasts which might reduce the possibility of hypertrophyic scaring, and improve wound healing.

[Effects of dermal template on the biological behaviors of fibroblasts during wound healing] Publishing Authors By Initials

Y Liu,S Lu,C Qing,Z Liao,J Shi,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

[Effects of dermal template on the biological behaviors of fibroblasts during wound healing] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhonggu

VOLUME: 19

Page Numbers: 10-4

Journal Abbreviation:

ISSN: 1002-1892

DAY: 11

MONTH: Jan

YEAR: 2005

[Effects of dermal template on the biological behaviors of fibroblasts during wound healing] Information

Number of References:

LANGUAGE: chi

NlmUniqueID: 9425194

[Effects of dermal template on the biological behaviors of fibroblasts during wound healing] Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: [Effects of dermal template on the biological behaviors of fibroblasts during wound healing] Information

Substance Name:

Registry Number:

Grant and Affiliation Information for [Effects of dermal template on the biological behaviors of fibroblasts during wound healing]

AFFILIATION: Department of Burns, Burn Institute of Shanghai, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, P R China.

Country: China

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Zhongguo Xiu Fu Chong Jian Wai

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Effects of dermal template on the biological behaviors of fibroblasts during wound healing Related Publications

• [A further study on the correlation between molar response value and molecular connectivity indices]
• [A study on the adduct characteristics of styrene and DNA]
• [A study on the effect and mechanism of acupuncture suppression of neuronal apoptosis following cerebral ischemia]
• [An experimental study on the effects of postburn dietary supplementation of enhanced nutrients]
• [Comparison of the toxic effect of methamidophos and acephate on acetylcholinesterase]
• [Concentration dependence of luminescence under different excitation wavelength in Y2O2S:Sm3+ phosphor]
• [Determination of composition of electronic material by fundamental parameter method of XRF]
• [Determination of lead in human hair using flame atomic absorption spectrometry and nebulization assisted with hydride generation]
• [Determination of tau-fluvalinate residue in honey by GC]
• [Determining mole ratio of monomers in new adsorbent of solid-phase microextraction by infrared spectroscopy]
• [Deviation of size-exclusion chromatographic behavior of tryptophan on TOYOPEARL HW-40S column]
• [Effects of dermal template on the biological behaviors of fibroblasts during wound healing]
• [Evaluation of mastication function after three-dimensional maxillary reconstruction]
• [Experimental study on the proportion of three nutrients in burn rats with enteral nutrition]
• [Four cases of meconium peritonitis in infants]
• [Gas chromatographic analysis of fatty acids in phosphatidylglycerol from needles of two crosses of Chinese Fir]
• [History of surgery for breast cancer]
• [ICP-AES method for the determination of active components Mo and Bi in catalyst for acrylonitrile production]
• [Influence of tangential excision within 24 postburn hours on the local wound inflammatory response in patients with deep partial thickness burn]
• [Initiation of systemic administration of antibiotics in treatment of invasive infection of burns]
• [Parental education to reduce blood lead levels in children with mild and moderate lead poisoning: a randomized controlled study]
• [Possible association between 278C/A single nucleotide polymorphism of FKBP6 and idiopathic azoospermia]
• [Pre-operation evaluation and intra-operation management of cochlear implantation]
• [Simulation study of the reconstruction algorithm for electrical impedance tomography based on the sensitivity theorem]
• [Studies of bone marrow T lymphocytes in patients with aplasic anemia]
• [Study on the distributed integration of the HIS and PACS based on CORBA]
• [The biological effect of tetrahydrobiopterin and its potential role in sepsis]
• [The identification of mouse cloned SFA DNA]
• [The influence of L-arginine on the angiogenesis in burn wounds in diabetic rats]
• [Treatment and restoration of residual root and crown: Part I. Factors involved in preservation of residual crown and root]