Effects of calcium phosphate nanoparticles on Ca-PO4 composite.

Effects of calcium phosphate nanoparticles on Ca-PO4 composite. Research Abstract Details 

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Effects of calcium phosphate nanoparticles on Ca-PO4 composite. Abstract Text:

H H K Xu,M D Weir,L Sun,S Takagi,L C Chow,

Nano-particles of dicalcium phosphate anhydrous (DCPA) were synthesized for the first time. The objectives of this study were to incorporate DCPA nano-particles into resin for Ca-PO(4) release to combat dental caries, and to investigate the filler level effects. Nano-DCPA and nano-silica-fused silicon nitride whiskers at a 1:1 ratio were used at filler mass fractions of 0-75%. The flexural strengths in MPa (mean +/- SD; n = 6) of DCPA-whisker composites ranged from (106 +/- 39) at 0% fillers to (114 +/- 23) at 75% fillers, similar to (112 +/- 22) of a non-releasing composite (TPH) (p > 0.1). The composite with 75% fillers in a NaCl solution (133 mmol/L, pH = 7.4, 37 degrees C) yielded a Ca concentration of (0.65 +/- 0.02) mmol/L and PO(4) of (2.29 +/- 0.07) mmol/L. Relationships were established between ion-release and DCPA volume fraction V(DCPA): Ca = 4.46 V(DCPA)(1.6,) and = 66.9 V(DCPA)(2.6). Nano-DCPA-whisker PO(4) composites had high strength and released high levels of Ca-PO(4) requisite for remineralization. These new nano-composites could provide the needed combination of stress-bearing and caries-inhibiting capabilities.

Effects of calcium phosphate nanoparticles on Ca-PO4 composite. Publishing Authors By Initials

HH Xu,MD Weir,L Sun,S Takagi,LC Chow,

For similar dentistry: tooth remineralization research abstracts see: dentistry: tooth remineralization research

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Effects of calcium phosphate nanoparticles on Ca-PO4 composite. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of dental research

VOLUME: 86

Page Numbers: 378-83

Journal Abbreviation: J. Dent. Res.

ISSN: 0022-0345

DAY: 3

MONTH: Apr

YEAR: 2007

Effects of calcium phosphate nanoparticles on Ca-PO4 composite. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 354343

Effects of calcium phosphate nanoparticles on Ca-PO4 composite. Keywords Mesh Terms:

KEYWORDS: Tooth Remineralization

MESH TERMS: methods

Chemical & Substance for Abstract: Effects of calcium phosphate nanoparticles on Ca-PO4 composite. Information

Substance Name: dicalcium phosphate anhydrous

Registry Number: 7757-93-9

Grant and Affiliation Information for Effects of calcium phosphate nanoparticles on Ca-PO4 composite.

AFFILIATION: Paffenbarger Research Center, American Dental Association Foundation, National Institute of Standards and Technology, Building 224, Room A-153, Stop 8546, Gaithersburg, MD 20899-8546, USA. hockin.xu@nist.gov

Country: United States

AGENCY: United States NIDCR

GRANT: R01 DE14190

ACRONYM: DE

MEDLINETA: J Dent Res

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