Special Feature

User Panel

My Panel

My Panel

Bookmark Science Articles

Recent News
Bookmark / Share This Science Site

Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure.

Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

  • Abstract Text of This Paper
  • Journal Published
  • MeSH Keywords of This Abstract
  • Chemicals and Substances Used in this Paper
  • Grants and Granting Agency of this Research
  • Database Accession Numbers Used in this Paper
  • Related Papers
  • Related Research Tags
  • Rate this Research Paper
  • Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure. Abstract Text:

    t yamaguchiT Yamaguchi,m matsumotoM Matsumoto,e kimotoE Kimoto,

    Effects of anion transport inhibitors on hemolysis of human erythrocytes at 200 mPa were examined. The degree of hemolysis was decreased by treating intact cells with 4,4'-diisothiocyanostilbene-2,2'-disulfonate (DIDS), 4,4'-dinitrostilbene-2,2'-disulfonate and pyridoxal 5'-phosphate (PLP) had little effect on the hemolysis. In contrast, the degree of hypotonic hemolysis increased upon treatment with anion transport, inhibitors. From the relationship between the hemolysis at 200 mPa and anion transport, it was found that high-pressure-induced hemolysis was suppressed by the covalent binding of anion transport inhibitors to band 3. This idea was supported by the finding that the hemolysis at 200 mPa of trypsin-treated erythrocytes was suppressed by DIDS. Furthermore, the spectrin content in vesicles which are released from erythrocyte ghost by dimyristoyl-phosphatidylcholine decreased upon DIDS labeling of band 3, but did not change upon PLP labeling. These results suggest that the interaction of the cytoplasmic domain of band 3 with spectrin, perhaps via ankyrin, is tightened by the covalent binding of bulky ligands to the exofacial domain of band 3.

    Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure. Publishing Authors By Initials

    t yamaguchiT Yamaguchi,m matsumotoM Matsumoto,e kimotoE Kimoto,

    For similar organic chemicals: imides: succinimides research abstracts see: organic chemicals: imides: succinimides research

    PUBMED ID PMID:

    MEDLINE DATE:

    Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Journal of biochemistry

    VOLUME: 118

    Page Numbers: 760-4

    Journal Abbreviation: J. Biochem.

    ISSN: 0021-924X

    DAY: 19

    MONTH: Oct

    YEAR: 1995

    Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 376600

    Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure. Keywords Mesh Terms:

    KEYWORDS: Succinimides

    MESH TERMS: pharmacology

    Chemical & Substance for Abstract: Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure. Information

    Substance Name: bis(sulfosuccinimidyl)suberate

    Registry Number: 82436-77-9

    Grant and Affiliation Information for Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure.

    AFFILIATION: Department of Chemistry, Faculty of Science, Fukuoka University.

    Country: JAPAN

    JAPAN Research PublicationJAPAN Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: J Biochem

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

    Effects of anion transport inhibitors on hemolysis of human erythrocytes under hydrostatic pressure Related Publications

     

    Molecular Station USER Menu

    Welcome to Molecular Station!

    You have to register before you can post on our forums or use our advanced features. Register Now! Its Free and Fast!

    Already registered? Login now below.

    User Name:

    Password:

    Already registered and Forgot your password? Click below to recover it.

    Recover Lost Password

    Join now - it's fast and free!

    Molecular Station is THE largest network of researchers, scientists and science lovers anywhere!

    Research Terms of Usage and Disclaimer
    Home
    Features

    Protocols

    DNA Forum

    Science Forum

    DNA Forum
    Biology Forum

    Science News


    [CaRP] XML error: Invalid document end at line 2

    For more click here:Science News