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[Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals]

[Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals] Research Abstract Details 

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  • [Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals] Abstract Text:

    j sinadinovi?J Sinadinovi?,d cveji?D Cveji?,s savinS Savin,j v mi?i?J V Mi?i?,

    Amiodarone is a benzofurane derivative which contains an appreciable amount of iodine (37%). It is used in cardiology as an antianginal and antiarrhythmic drug. Using guinea-pigs and rats as the animal model systems, the effects of amiodarone on normal and hyperplastic thyroid glands were investigated in eu- and hypothyroid animals. After the amiodarone treatment, considerable differences were observed in the levels of thyroid hormones and in the structure of the gland which proved dependent not only on the length of treatment, but also on animal species and the functional status of the gland before treatment. At extended amiodarone application, the rats with hyperplastic thyroid developed microlesions in epithelium of some follicles.

    [Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals] Publishing Authors By Initials

    j sinadinovi?J Sinadinovi?,d cveji?D Cveji?,s savinS Savin,jv mi?i?JV Mi?i?,

    For similar hormones, hormone substitutes, and hormone antagonists: hormones: thyroid hormones research abstracts see: hormones, hormone substitutes, and hormone antagonists: hormones: thyroid hormones research

    PUBMED ID PMID:

    MEDLINE DATE:

    [Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Glas. Srpska akademija nauka i umetnosti. Odeljenj

    VOLUME:

    Page Numbers: 93-105

    Journal Abbreviation:

    ISSN: 0081-3966

    DAY: 7

    MONTH: 12

    YEAR: 1992

    [Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals] Information

    Number of References:

    LANGUAGE: scc

    NlmUniqueID: 27437

    [Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals] Keywords Mesh Terms:

    KEYWORDS: Thyroid Hormones

    MESH TERMS: blood

    Chemical & Substance for Abstract: [Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals] Information

    Substance Name: Amiodarone

    Registry Number: 1951-25-3

    Grant and Affiliation Information for [Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals]

    AFFILIATION:

    Country: YUGOSLAVIA

    YUGOSLAVIA Research PublicationYUGOSLAVIA Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Glas Srp Akad Nauka [Med]

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

    Effects of amiodarone on the thyroid gland in euthyroid and hypothyroid animals Related Publications

     

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