[Effect on xenograft of nude mouse by combination therapy of nm23-H1 and protein-cisplatin]

[Effect on xenograft of nude mouse by combination therapy of nm23-H1 and protein-cisplatin] Research Abstract Details 

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[Effect on xenograft of nude mouse by combination therapy of nm23-H1 and protein-cisplatin] Abstract Text:

Ke-Qian Zhi,Wei-Hui Chen,Yu-Ming Wen,

OBJECTIVE: To study the effect of protein-cisplatin and nm23-H1 therapy on the tumor of nude mouse. METHODS: The 15 BALB/C female mice were divided into three groups, control group, protein-cisplatin group and protein-cisplatin+nm23-H1 plasmid group. Tca8113 were injected into the mice subcutaneously with the concentration of 3.1 x 10(6) cells/mL. After two weeks, the mixture of lipofectin and nm23-H1 was injected around xenograft of nude mouse. After three days, the protein-cisplatin was injected around xenograft. The weight of mouse, the volume and the weight of xenograft were measured. RESULTS: The weight of mouse was lightest in control group. The volume and weight of the transplanted tumor were lightest in nm23-H1 +protein-cisplatin group. CONCLUSION: The combination therapy of nm23-H1 and protein-cisplatin can effectively inhibites the growth of xenograft in nude mouse.

[Effect on xenograft of nude mouse by combination therapy of nm23-H1 and protein-cisplatin] Publishing Authors By Initials

KQ Zhi,WH Chen,YM Wen,

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[Effect on xenograft of nude mouse by combination therapy of nm23-H1 and protein-cisplatin] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yi

VOLUME: 24

Page Numbers: 170-2

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ISSN: 1000-1182

DAY: 17

MONTH: Apr

YEAR: 2006

[Effect on xenograft of nude mouse by combination therapy of nm23-H1 and protein-cisplatin] Information

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LANGUAGE: chi

NlmUniqueID: 9422648

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AFFILIATION: Dept. of Oral and Maxillofacial Surgery, College of Stomatology, Xi'an Jiaotong University, Xi'an 710004, China.

Country: China

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MEDLINETA: Hua Xi Kou Qiang Yi Xue Za Zhi

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