Effect of vitamin E eye drops on naphthalene-induced cataract in rats.

Effect of vitamin E eye drops on naphthalene-induced cataract in rats. Research Abstract Details 

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Effect of vitamin E eye drops on naphthalene-induced cataract in rats. Abstract Text:

M Nagata,M Kojima,K Sasaki,

The effect of vitamin E acetate (VEA) eye drops on naphthalene-induced cataract in rats was investigated by Scheimpflug image analysis. The control group was administered only naphthalene (1 g/kg), while the other group was additionally given 1% VEA eye drops into both eyes 5 times a day every day for 9 weeks from the start of naphthalene treatment. During those 9 weeks, the changes of the crystalline lens were documented by an anterior eye segment analysis system (EAS-1000, NIDEK) once a week in mydriasis (Mydrin-P, Santen Pharmaceutical Co., Ltd.). The characteristic density values of the anterior deeper cortex regions were measured. The light scattering intensity of lenses from VEA eye drop-treated animals was significantly lower than that of animals without VEA treatment. This difference was found 1 week, 4 weeks, and from 7 to 9 weeks after the start of naphthalene application. VEA eye drops may have the potential to delay the progression of naphthalene-induced cataract in rats.

Effect of vitamin E eye drops on naphthalene-induced cataract in rats. Publishing Authors By Initials

M Nagata,M Kojima,K Sasaki,

For similar heterocyclic compounds: heterocyclic compounds, 2-ring: benzopyrans: vitamin e: tocopherols: alpha-tocopherol research abstracts see: heterocyclic compounds: heterocyclic compounds, 2-ring: benzopyrans: vitamin e: tocopherols: alpha-tocopherol research

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Effect of vitamin E eye drops on naphthalene-induced cataract in rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of ocular pharmacology and therapeutics :

VOLUME: 15

Page Numbers: 345-50

Journal Abbreviation:

ISSN: 1080-7683

DAY: 19

MONTH: Aug

YEAR: 1999

Effect of vitamin E eye drops on naphthalene-induced cataract in rats. Information

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LANGUAGE: eng

NlmUniqueID: 9511091

Effect of vitamin E eye drops on naphthalene-induced cataract in rats. Keywords Mesh Terms:

KEYWORDS: alpha-Tocopherol

MESH TERMS: analogs & derivatives

Chemical & Substance for Abstract: Effect of vitamin E eye drops on naphthalene-induced cataract in rats. Information

Substance Name: naphthalene

Registry Number: 91-20-3

Grant and Affiliation Information for Effect of vitamin E eye drops on naphthalene-induced cataract in rats.

AFFILIATION: Department of Ophthalmology, Kanazawa Medical University, Uchinada, Ishikawa, Japan.

Country: UNITED STATES

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MEDLINETA: J Ocul Pharmacol Ther

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