[Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity]

[Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity] Research Abstract Details 

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[Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity] Abstract Text:

M A Pilinskaia,L S Stepanova,

Investigation of a cytogenetic activity of the insecticide carbofuran and its three main metabolites formed in the mammals' organisms and in the environmental objects showed that the initial substance and two intermediate products of its biotransformation (3-hydroxycarbofuran and 3-keto-carbofuran) induced a clastogenic effect in the culture of human peripheral lymphocytes in vitro. The end metabolite (3-keto-7-phenol) had no mutagenic effect in vitro. The data obtained give evidence for disappearance of the carbofuran mutagenicity in the course of its biotransformation in mammals.

[Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity] Publishing Authors By Initials

MA Pilinskaia,LS Stepanova,

For similar plants research abstracts see: plants research

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[Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: T?Sitologii?a i genetika

VOLUME: 18

Page Numbers: 17-20

Journal Abbreviation:

ISSN: 0564-3783

DAY: 15

MONTH: 02

YEAR: 2008

[Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity] Information

Number of References:

LANGUAGE: rus

NlmUniqueID: 101671

[Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity] Keywords Mesh Terms:

KEYWORDS: Plants

MESH TERMS: metabolism

Chemical & Substance for Abstract: [Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity] Information

Substance Name: Carbofuran

Registry Number: 1563-66-2

Grant and Affiliation Information for [Effect of the biotransformation of the insecticide furadan on in vivo and in vitro manifestations of its cytogenetic activity]

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Country: USSR

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MEDLINETA: Tsitol Genet

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