We studied the effect of potentiated antibodies to morphine (10(-100) wt %) on self-stimulation of the lateral hypothalamus and behavioral reactions reflecting the severity of withdrawal syndrome in rats with morphine dependence. Repeated treatment with potentiated antibodies to morphine increased the rate of self-stimulation, suppressed active avoidance response, promoted freezing behavior after acoustic stimulation, and decreased tail-flick latency in rats after morphine withdrawal. Distilled water did not produce these changes.
Effect of potentiated antibodies to morphine on behavioral reactions in rats with morphine dependence. Publishing Authors By Initials
Effect of potentiated antibodies to morphine on behavioral reactions in rats with morphine dependence. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Bulletin of experimental biology and medicine
VOLUME: 135 Suppl 1
Page Numbers: 34-5
Journal Abbreviation: Bull. Exp. Biol. Med.
ISSN: 0007-4888
DAY: 1
MONTH: 09
YEAR: 2003
Effect of potentiated antibodies to morphine on behavioral reactions in rats with morphine dependence. Information
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LANGUAGE: eng
NlmUniqueID: 372557
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Grant and Affiliation Information for Effect of potentiated antibodies to morphine on behavioral reactions in rats with morphine dependence.
AFFILIATION: Institute of Neurology, Psychiatrics, and Narcology, Ukrainian Academy of Medical Sciences, Kharkov; "Materia Medica Holding" Research-and-Production Company, Moscow.
Country: United States
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MEDLINETA: Bull Exp Biol Med
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