[Effect of immunostimulatory sequence on the expression of EOTAXIN of experimental allergic rhinitis]

[Effect of immunostimulatory sequence on the expression of EOTAXIN of experimental allergic rhinitis] Research Abstract Details 

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[Effect of immunostimulatory sequence on the expression of EOTAXIN of experimental allergic rhinitis] Abstract Text:

Jianjun Chen,Weijia Kong,Jisheng Xiang,

OBJECTIVE: To investigate the effect of CpG DNA applied intraperitoneally on the expression of EOTAXIN of allergic rhinitis model. METHOD: CpG DNA was injected intraperitoneally to rat at the same time of the basic intraperitoneal immunized. The symptoms, expression of eosinophil (EOS) in nasal cavity and expression of EOTAXIN in the nasal mucosa were measured. RESULT: After the CpG DNA was applied, the symptom scores, eosinophil (EOS) in nasal cavity and expression of EOTAXIN were weaken. CONCLUSION: There was great reverse effect of CpG DNA on the foundation of rat model of experimental allergic rhinitis, suppression of EOTAXIN may be one of the mechanisms.

[Effect of immunostimulatory sequence on the expression of EOTAXIN of experimental allergic rhinitis] Publishing Authors By Initials

J Chen,W Kong,J Xiang,

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[Effect of immunostimulatory sequence on the expression of EOTAXIN of experimental allergic rhinitis] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Lin chuang er bi yan hou ke za zhi = Journal of cl

VOLUME: 20

Page Numbers: 362-4

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ISSN: 1001-1781

DAY: 14

MONTH: Apr

YEAR: 2006

[Effect of immunostimulatory sequence on the expression of EOTAXIN of experimental allergic rhinitis] Information

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LANGUAGE: chi

NlmUniqueID: 9426080

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AFFILIATION: Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan, 430022, China. jj-c@tom.com

Country: China

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MEDLINETA: Lin Chuang Er Bi Yan Hou Ke Za

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