[Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line]

[Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line] Research Abstract Details 

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[Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line] Abstract Text:

Huan-min Luo,Hui Deng,Feng Huang,Fei Xiao,Xiao-guang Li,Pei-fen Zhang,Qin Gao,Wen Weng,

OBJECTIVE: To investigate the effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line. METHOD: MTT was used to measure the levels of the survival rate of BT325 cultured with ginsenoside Rg1 and LPS in different concentrations. The expression of NEP was measured by RT-PCR. RESULT: The survival rate of BT325 was obviously inhibited by LPS, and the expression of NEP was decreased. The survival rate of BT325 was obviously raised by ginsenoside Rg1, and the expression of NEP was increased. CONCLUSION: LPS can cause cell damage, and decrease the expression of NEP. Ginsenoside Rg1 can exert neuroprotective properties which protects BT325 cell line from the cell toxicity of LPS.

[Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line] Publishing Authors By Initials

HM Luo,H Deng,F Huang,F Xiao,XG Li,PF Zhang,Q Gao,W Weng,

For similar plants: plants, medicinal research abstracts see: plants: plants, medicinal research

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[Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazh

VOLUME: 29

Page Numbers: 890-3

Journal Abbreviation: Zhongguo Zhong Yao Za Zhi

ISSN: 1001-5302

DAY: 6

MONTH: Sep

YEAR: 2004

[Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line] Information

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LANGUAGE: chi

NlmUniqueID: 8913656

[Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line] Keywords Mesh Terms:

KEYWORDS: Plants, Medicinal

MESH TERMS: chemistry

Chemical & Substance for Abstract: [Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line] Information

Substance Name: Neprilysin

Registry Number: EC 3.4.24.11

Grant and Affiliation Information for [Effect of ginsenoside Rg1 on the influence of neprilysin expression induced by LPS in BT325 cell line]

AFFILIATION: Neuropharmacological Research Laboratory, College of Pharmacy, Jinan University, Guangzhou 510632, China. tlhm@jnu.edu.cn

Country: China

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MEDLINETA: Zhongguo Zhong Yao Za Zhi

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