Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate.

Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. Abstract Text:

Takafumi Kohama,Kotaro Herai,Masaki Inoue,Takafumi Kohama,Kotaro Herai,Masaki Inoue,

OBJECTIVE: To clarify the effect of Pycnogenol (Horphag Research, Geneva, Switzerland), French maritime pine bark extract, on endometriosis. STUDY DESIGN: Fifty-eight women were included in this study. They were operated on conservatively for endometriosis and surgically diagnosed with the condition. All patients were followed at 4, 12, 24 and 48 weeks after starting treatment to check for endometriosis signs and symptoms, including changes in CA-125 and estrogen levels (E2). Thirty-two patients in the Pycnogenol treatment group took 60 mg Pycnogenol orally a day for 48 weeks. The 26 patients who received gonadotropin-releasing hormone agonist (Gn-RHa) were treated in the standard way. RESULTS: Treatment with Pycnogenol slowly but steadily reduced the symptom scores. Treatment with Gn-RHa reduced the scores more efficiently; however, 24 weeks after the end of treatment, the scores suggested a recurrence of signs. No influence of treatment on menstrual cycles or E2 was observed in the Pycnogenol group. CA-125 decreased in both treatment groups. Patients with smaller endometriomas responded better to treatment as compared to patients with larger endometriomas. In the Gn-RHa group, the lowering of CA-125 concentrations was far more pronounced; however, a clear rebound effect was observed. CONCLUSION: Pycnogenol is a therapeutic alternative to Gn-RHa in the treatment of endometriosis.

Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. Publishing Authors By Initials

T Kohama,K Herai,M Inoue,T Kohama,K Herai,M Inoue,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of reproductive medicine

VOLUME: 52

Page Numbers: 703-8

Journal Abbreviation:

ISSN: 0024-7758

DAY: 20

MONTH: Aug

YEAR: 2007

Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 173343

Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate.

AFFILIATION: Department of Obstetrics and Gynecology, Keiju Medical Center, Tomioka-chou 94, Nanao City, Ishokawa, Japan. kohama@yu.include.ne.jp

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Reprod Med

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate Related Publications

• A 'reverse' phylogenetic approach for identification of novel osmoregulatory and cardiovascular hormones in vertebrates.
• Determination of microscopic ionization constants and microscopic stacking equilibrium quotients of adenylyl(3' --> 5')adenosine.
• Development of a micropulverized extraction method for rapid toxicological analysis of methamphetamine in hair.
• Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate.
• Expression of Dmp1 in specific differentiated, nonproliferating cells and its regulation by E2Fs.
• Factors Contributing to Cavitation after CT-guided Percutaneous Radiofrequency Ablation for Lung Tumors.
• Hardness and elasticity of sound and caries-affected primary dentin bonded with one-step self-etch adhesive.
• Increased expression of ephrin A1 in brain arteriovenous malformation: DNA microarray analysis.
• Influence of playing wind instruments on activity of masticatory muscles.
• Inter-observer variations in FDG-PET interpretation for cancer screening.
• Intervertebral disc degeneration: biological and biomechanical factors.
• Lack of mitochondrial DNA enhances growth of hepatocellular carcinoma in vitro and in vivo.
• Mannose-conjugated alendronate selectively depletes Kupffer cells and inhibits endotoxemic shock in the mice.
• Mechanical properties of comonomer-compositionally fractionated poly[(3-hydroxybutyrate)-co-(3-mercaptopropionate)] with low 3-mercaptopropionate unit content.
• Microcirculation in eyes after rhegmatogenous retinal detachment surgery.
• Microembolic signals are associated with progression of arterial lesion in Moyamoya disease: a case report.
• Neurosprora crassa RAD5 homologue, mus-41, inactivation results in higher sensitivity to mutagens but has little effect on PCNA-ubiquitylation in response to UV-irradiation.
• Novel correction methods as alternatives for the six-dimensional correction in CyberKnife treatment.
• Organelles containing inositol trisphosphate receptor type 2 in adrenal medullary cells.
• Pharmacological cardioversion of long-lasting atrial fibrillation.
• Radiological follow-up study of rheumatoid wrists after radio-lunate limited arthrodesis with ulnar head resection.
• Relation of interleukin-6 and C-reactive protein levels to sinus maintenance after pharmacological cardioversion in persistent atrial fibrillation.
• Spatiotemporal localization of germ plasm RNAs during zebrafish oogenesis.
• Spin transition at the mesophase transition temperature in a cobalt(II) compound with branched alkyl chains.
• Suppression of viral replication by stress-inducible GADD34 protein via the mammalian serine/threonine protein kinase mTOR pathway.
• Thioredoxin overexpression in mice, model of attenuation of oxidative stress, prevents benzene-induced hemato-lymphoid toxicity and thymic lymphoma.
• Tumour necrosis factor alpha-stimulated gene-6 inhibits osteoblastic differentiation of human mesenchymal stem cells induced by osteogenic differentiation medium and BMP-2.
• Visual reflex seizures induced by complex stimuli.
• [Current and future prospects for anti-osteoporotic drugs]
• [Syntheses and spectra of Mn(III)-chlorophyll-a and Mn(II)-chlorophyll-a]