Effect of excessive iodine on immune function of lymphocytes and intervention with selenium.

Effect of excessive iodine on immune function of lymphocytes and intervention with selenium. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Effect of excessive iodine on immune function of lymphocytes and intervention with selenium. Abstract Text:

Xiaoyi Chen,Liegang Liu,Ping Yao,Dong Yu,Liping Hao,Xiufa Sun,

In order to study the effect of excessive iodine on immune function of lymphocytes and the role of selenium supplementation with excessive iodine intake, the changes of T lymphocyte number, ratio of subsets, activity of natural killer (NK) cells and lymphocytes proliferation response were investigated. 150 female BALB/C mice were randomly divided into 5 groups in terms of their body weight (n=30 in each group), and 10 of each group were taken as one batch for test. Mice in the 5 groups were orally administrated with iodine 0 (group I), 1500 (group II), 3000 (group III), 6000 microg/L (group IV), iodine 6000 microg/L plus selenium 0.3 mg/L (group V) respectively for 30 days Lymphocyte proliferation response, CD4(+)/CD8(+), Th1/Th2 and the activity of NK cells were measured. CD4(+)/CD8(+) was significantly lower, while lymphocyte proliferation response stronger, and Th1/Th2 and the activity of NK cells significantly higher in group IV than in group I (P<0.01). There was no significant difference in all indexes between group V and group I (P>0.05). It was suggested that excessive iodine as exogenous chemical materials can induce disorders of T lymphocyte immune function in mice. 0.3 mg/L selenium supplementation can protect mice against toxicity induced by 6000 microg/L iodine.

Effect of excessive iodine on immune function of lymphocytes and intervention with selenium. Publishing Authors By Initials

X Chen,L Liu,P Yao,D Yu,L Hao,X Sun,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Effect of excessive iodine on immune function of lymphocytes and intervention with selenium. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of Huazhong University of Science and Tech

VOLUME: 27

Page Numbers: 422-5

Journal Abbreviation: J. Huazhong Univ. Sci. Technol

ISSN: 1672-0733

DAY: 10

MONTH: Aug

YEAR: 2007

Effect of excessive iodine on immune function of lymphocytes and intervention with selenium. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101169627

Effect of excessive iodine on immune function of lymphocytes and intervention with selenium. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Effect of excessive iodine on immune function of lymphocytes and intervention with selenium. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Effect of excessive iodine on immune function of lymphocytes and intervention with selenium.

AFFILIATION: Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. wchenxy1@126.com

Country: China

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Huazhong Univ Sci Technolog

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Effect of excessive iodine on immune function of lymphocytes and intervention with selenium Related Publications

• Circadian clock genes oscillate in human peripheral blood mononuclear cells.
• Lumbar spinal fusion with a mineralized collagen matrix and rhBMP-2 in a rabbit model.
• Regulatory peptides modulate ICAM-1 gene expression and NF-kappaB activity in bronchial epithelial cells.
• [A comparative study of EGFR and FGFR-2 expression in fetal and adult skin]
• [A monitoring study of electromyography median frequency on fatigue of erector spinalis in drivers working at high altitude]
• [Achievements in the research on filariasis in China in the past 50 years]
• [An experiment to study the treatment of sarcomas by electroporation]
• [An observation of the effects of Tiopronin on the oxygen free radicals in severely scalded rats receiving delayed fluid resuscitation]
• [Analysis on genetic polymorphism of 14 short tandem repeat loci on chromosome 7p14-15 and 12q13 in Chinese north Hans]
• [Application of noninvasive hemodynamic monitoring in patients with heart failure caused by chronic pulmonary heart diseases]
• [Colocalization of 11beta-hydroxysteroid dehydrogenase type I and glucocorticoid receptor and its significance in rat hippocampus]
• [Effect of "yang wei kang liu" granula on expression of P53 and PCNA in mice bearing sarcoma 180]
• [Effects of ATP concentration and hypoxic exposure on RNA and protein synthesis activity in isolated mitochondria from rat brain]
• [Effects of Ulinastatin on the intestinal mucosal barrier of the mini-pigs after severe burn injury]
• [Expression of recombinant human Flt3 ligand in Escherichia coli and its purification and characterization]
• [Expression of transporter associated with antigen processing (TAP) in childhood acute leukemia and its clinical significance]
• [Influence of prostaglandin E2 on proliferation of melanocytes in full-thickness skin graft]
• [Investigation and evaluation on the harmfulness of partial vibration and the contact vibration time]
• [Okadaic acid induces the expression of glutamate transporter EAAT1 in the neurons of rat brain]
• [Pathology and pathophysiology of severe acute respiratory syndrome]
• [Protective effect of exogenous bcl-2 on spinal cord motoneurons following sciatic nerve axotomy in the rat]
• [Risk factors for malignant pleural mesothelioma in crocidolite contaminated area]
• [Selection of vestibular system function in Chinese astronauts]
• [Spatial autocorrelation analysis on schistosomiasis cases and Oncomelania snails in three provinces of the lower reach of Yangtze River]
• [Studies on crosslinkable coatings for biomedical application]
• [Study on the relationship between the opacity of lens and the levels of 2, 6-dinitro-4-amino-toluene (DNAT) in the urine of workers exposed to trinitrotoluene(TNT)]
• [The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese]
• [The effects of NO inhalation on cardice function in the burn patients with inhalation injury]
• [The expression of nestin in ischemia-injured brain of adult rat]
• [The neuromuscular transmission effects induced by pralidoxine chloride on rats with acute isocarbophos poisoning]