Effect of continuous display of cerebral perfusion pressure on outcomes in patients with traumatic brain injury.

Effect of continuous display of cerebral perfusion pressure on outcomes in patients with traumatic brain injury. Research Abstract Details 

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Effect of continuous display of cerebral perfusion pressure on outcomes in patients with traumatic brain injury. Abstract Text:

Catherine J Kirkness,Robert L Burr,Kevin C Cain,David W Newell,Pamela H Mitchell,

BACKGROUND: Clinical bedside monitoring systems do not provide prominent displays of data on cerebral perfusion pressure (CPP). Immediate visual feedback would allow more rapid intervention to prevent or minimize suboptimal pressures. OBJECTIVE: To evaluate the effect of a highly visible CPP display on immediate and long-term functional outcome in patients with traumatic brain injury. METHODS: A total of 157 patients with traumatic brain injury at a level 1 trauma center who had invasive arterial blood pressure and intracranial pressure monitoring were randomized to beds with or without an additional, prominent continuous CPP display. Primary end points were scores on the Extended Glasgow Outcome Scale (GOSE) and Functional Status Examination (FSE) 6 months after injury. Secondary end points were GOSE scores at discharge and 3 months after injury and FSE score 3 months after injury. RESULTS: Although GOSE and FSE scores at 6 months were better in the group with the highly visible CPP display, the differences were not significant. Slope of recovery for GOSE and FSE over all follow-up time points did not differ significantly between groups. However, the intervention's positive effect on odds of survival at hospital discharge was strong and significant. Within a subgroup of more severely injured patients, the intervention group was much less likely than the control group to have CPP deviations. CONCLUSIONS: The presence of a highly visible display of CPP was associated with significantly better odds of survival and overall condition at discharge.

Effect of continuous display of cerebral perfusion pressure on outcomes in patients with traumatic brain injury. Publishing Authors By Initials

CJ Kirkness,RL Burr,KC Cain,DW Newell,PH Mitchell,

For similar investigative techniques: epidemiologic methods: statistics as topic: survival analysis research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: survival analysis research

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Effect of continuous display of cerebral perfusion pressure on outcomes in patients with traumatic brain injury. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: American journal of critical care : an official pu

VOLUME: 15

Page Numbers: 600-9; quiz 610

Journal Abbreviation: Am. J. Crit. Care

ISSN: 1062-3264

DAY: 3

MONTH: Nov

YEAR: 2006

Effect of continuous display of cerebral perfusion pressure on outcomes in patients with traumatic brain injury. Information

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LANGUAGE: eng

NlmUniqueID: 9211547

Effect of continuous display of cerebral perfusion pressure on outcomes in patients with traumatic brain injury. Keywords Mesh Terms:

KEYWORDS: Survival Analysis

MESH TERMS: nursing

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Grant and Affiliation Information for Effect of continuous display of cerebral perfusion pressure on outcomes in patients with traumatic brain injury.

AFFILIATION: Biobehavioral Nursing and Health Systems, University of Washington, Seattle, WA 98195-7266, USA. kirkness@u.washington.edu

Country: United States

AGENCY: United States NINR

GRANT: R01 NR04901

ACRONYM: NR

MEDLINETA: Am J Crit Care

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