Effect of Chinese herbal medicine on overactive bladder.

Effect of Chinese herbal medicine on overactive bladder. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Effect of Chinese herbal medicine on overactive bladder. Abstract Text:

Tetsuo Ogushi,Satoru Takahashi,

Gosha-jinki-gan (GJG), a traditional Chinese medicine, is known to be potentially effective for urinary disturbance. For the clinical evaluation of Gosha-jinki-gan, we administered GJG for 6 weeks to elderly male patients with overactive bladder (OAB) and assessed its efficacy and tolerability. In this study, 30 male patients with over 6 months of OAB symptoms had received 2.5 g GJG mixture x 3/day. After 6 weeks of treatment, the efficacy, safety, and tolerability were assessed. We evaluated International Prostate Symptom Score (I-PSS), Overactive Bladder Symptom Score (OABSS), quality of life (QOL), maximal urinary flow rate (Qmax), average urinary flow rate (Qave), incidence of urinary incontinence, and post-void residual before and after treatment. We observed significant improvements in I-PSS (15.2 +/- 1.0 vs. 12.0 +/- 0.9, p < 0.0001), OABSS (7.5 +/- 0.6 vs. 4.9 +/- 0.5, p < 0.0001), and QOL score (4.4 +/- 1.0 vs. 3.3 +/- 1.1, p < 0.0001, Wilcoxon rank sum test). GJG was significantly effective in improving urgency, micturition frequency, nocturia, and urinary incontinence (p < 0.05). However, Qmax, Qave, and post void residual did not significantly change. Mild adverse effects were observed in 3 cases. The symptoms were diarrhea, nausea, and urinary frequency. These data suggest that Gosha-jinki-gan may be a new potential therapeutic agent for OAB without deterioration of voiding function in men with benign prostatic obstruction (BPO).

Effect of Chinese herbal medicine on overactive bladder. Publishing Authors By Initials

T Ogushi,S Takahashi,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Effect of Chinese herbal medicine on overactive bladder. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Hinyokika kiyo. Acta urologica Japonica

VOLUME: 53

Page Numbers: 857-62

Journal Abbreviation:

ISSN: 0018-1994

DAY: 21

MONTH: Dec

YEAR: 2007

Effect of Chinese herbal medicine on overactive bladder. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 421145

Effect of Chinese herbal medicine on overactive bladder. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Effect of Chinese herbal medicine on overactive bladder. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Effect of Chinese herbal medicine on overactive bladder.

AFFILIATION: Department of Urology, Toshiba General Hospital.

Country: Japan

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Hinyokika Kiyo

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Effect of Chinese herbal medicine on overactive bladder Related Publications

• A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo.
• Bone morphogenetic protein 2 stimulates osteoclast differentiation and survival supported by receptor activator of nuclear factor-kappaB ligand.
• Circadian rhythms: the cancer connection.
• Comparison between stabilometry with and without head tilts in a roll plane.
• Effect of Escherichia coli wild type or its derivative with high nitrite reductase activity on in vitro ruminal methanogenesis and nitrate/nitrite reduction.
• Effect of gravity on apical dominance in Pharbitis nil.
• Effect of oral branched chain amino acid-rich nutrient administered during endoscopic injection sclerotherapy of cirrhotic patients.
• Forward genetic screens to identify circadian rhythm mutants in mice.
• Genome-wide epistatic interaction analysis reveals complex genetic determinants of circadian behavior in mice.
• Identification of the cDNA of differentially expressed genes in the transition zone of cucumber seedlings by fluorescent differential display.
• In vivo bone-forming capacity of human bone marrow-derived stromal cells is stimulated by recombinant human bone morphogenetic protein-2.
• Isolation of auxin efflux carrier cDNA from cucumber.
• Methods to record circadian rhythm wheel running activity in mice.
• Mice lacking smooth muscle calponin display increased bone formation that is associated with enhancement of bone morphogenetic protein responses.
• Mouse chimeras and their application to circadian biology.
• Novel hydrotropism mutants of Arabidopsis thaliana and their altered waving response and phototropism.
• Oral myiasis treated with ivermectin: case report.
• Osteoblasts provide a suitable microenvironment for the action of receptor activator of nuclear factor-kappaB ligand.
• Osteoprotegerin regulates bone formation through a coupling mechanism with bone resorption.
• Pax 2 expression in mesodermal segmentation and its relationship with EphA4 and Lunatic-fringe during chicken somitogenesis.
• Physiological and genetic characterization of hydrotropic mutants of Arabidopsis thaliana.
• Real-time luminescence reporting of circadian gene expression in mammals.
• Regulations: what next?
• The effect of light on the gravimorphogenesis of cucumber seedlings.
• The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude.
• [Bone morphogenetic protein (BMP): from basic studies to clinical approaches]
• [Differential expression of a homing-related molecule repertoire among umbilical cord blood, mobilized peripheral blood and bone marrow-derived hematopoietic stem/progenitor cells.]
• [Gravitaxis of paramecium: testing the hypotheses by free-fall experiments]
• [Sequence variability in Borna disease virus ORF II from human beings]
• [The effects of space environment on differentiation and mutation frequency in Dictyostelium discoideum]