Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone.

Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone. Abstract Text:

Yanping Chen,Bingshen Jia,Keqin Huang,Wenjie Zhang,Yan Xue,Chongguang Zhou,Wanqiang Zhang,

OBJECTIVE: To observe the effect of the serum containing Chengzai Pill on the L-type voltage-sensitive calcium channels current (L-VSCCsC) of osteoblastic MC3T3-E1 cells pretreated with methylprednisolone (mPSL). METHODS: A control group, a model group, a low dose group and a high dose group were set up. The whole cell patch clamp technique was used to record L-VSCCsC of 10 osteoblastic MC3T3-E1 cells in each group and their peak currents were determined. RESULTS: The peak current of the control group was 0.2284 +/- 0.0209 nA; the peak current of the model group was 0.1839 +/- 0.0179 nA; decreased by 19.5% as compared with the control group (P<0.01); the peak current of the low and high dose groups was 0.2526 +/- 0.0093 nA and 0.2671 +/- 0.0120 nA respectively, increased by 37.4% and 45.2% as compared with the model group (P<0.01); the difference between the low and high dose groups was P<0.05. CONCLUSION: 1. mPSL inhibits L-VSCCsC of osteoblasts; and 2. The serum containing Chengzai Pill increases L-VSCCsC of osteoblasts pretreated with mPSL.

Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone. Publishing Authors By Initials

Y Chen,B Jia,K Huang,W Zhang,Y Xue,C Zhou,W Zhang,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of traditional Chinese medicine = Chung i

VOLUME: 27

Page Numbers: 293-8

Journal Abbreviation:

ISSN: 0254-6272

DAY: 5

MONTH: Dec

YEAR: 2007

Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8211546

Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone.

AFFILIATION: Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China.

Country: China

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Tradit Chin Med

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Effect of chengzai pill on the L-type Ca2+ channel currents of osteoblasts pretreated with methylprednisolone Related Publications

• A comparative study on the intercuspal occlusion among TMD patients, malocclusion patients and university students.
• Effect of retinoblastoma gene on human osteosarcoma cell line OS732.
• Enhanced antioxidant and cytoprotective abilities of vitamin E succinate is associated with a rapid uptake advantage in rat hepatocytes and mitochondria.
• Intervention by azithromycin on bleomycin-induced lung injury in rats and its mechanisms.
• Method development of adsorbed stationary phase open tubular capillary electrochromatography.
• Supercritical fluid CO2 extraction of colchicine from colchicine Autumnele liliaceae.
• Vascular endothelial growth factor gene expression in patients' ischemic skeletal muscle with diabetic foot.
• [A case of hypodermiasis with empyema]
• [Analysis of hepatitis G virus genotypes in some areas of China]
• [Autologous dendritic cells eliciting cytotoxicity of bone marrow cells against chronic granulocytic leukemia]
• [Changes of human recombination bone morphogenetic protein-2 in bone and marrow in tail suspended rats]
• [Cloning of the mouse Doc-1R gene by genomic walking]
• [Construction of recombinant adenoviruses carrying human urokinase-type plasminogen activator and its expression in hepatic stellate cells in vitro]
• [Effect of inhibition of telomerase activity on cisplatin-induced apoptosis in K562 cells]
• [Effects of electrical stimulation of lateral hypothalamic area on gastric ischemia-reperfusion injury in rats]
• [Fatal complications in traffic accident injury]
• [Indomethacin induces apoptosis of K562 cells through activation of caspases and elevation of intracellular free calcium]
• [Infection and replication of hepatitis B virus and its clearance mechanism: an overview]
• [Mechanisms underlying dopaminergic neurotoxicity in ischemic cerebral damage]
• [Physiological and pathologic implications for zero-stress state of the esophagus]
• [Protein kinases and Alzheimer's disease]
• [Retroperitoneal laparoscopic unroofing of renal cyst: use of close method]
• [Risk of leukemia among medical X-ray workers in China between 1950 and 1995]
• [Studies on association between lipoprotein lipase gene polymorphisms of Pvu II site and hypertriglyceridemics in Chinese]
• [Study on automatic segmentation of color images applied to blood cells]
• [Study on high performance liquid chromatography/indirect photometric detection of fosfomycin with acridine as detection reagent]
• [Study on the application of number fluorescence density in detecting autoantibodies titer]
• [The effects of surface morphology of calcium phosphate ceramics on apatite formation in dynamic SBF]
• [Transforming growth factor beta(1) and bone morphogenetic protein 2 induce the differentiation of odontoblasts in vitro]
• [Vector propagation algorithm based ECG simulation of bundle branch block]