Effect of catenation on protein folding stability.

Effect of catenation on protein folding stability. Research Abstract Details 

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Effect of catenation on protein folding stability. Abstract Text:

Huan-Xiang Zhou,

Building on previous studies of the effects of covalent linking and backbone cyclization on protein folding stability, a theory is developed for the stabilization effect of catenating a dimeric protein. Relative to covalent linking, catenation is up to 1000-fold more powerful in stabilizing the folded structure. This dramatic stabilization derives from the dual effects of backbone cyclization and constrained relative motion between the subunits afforded by the catenane topology.

Effect of catenation on protein folding stability. Publishing Authors By Initials

HX Zhou,

For similar proteins research abstracts see: proteins research

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Effect of catenation on protein folding stability. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Chemical Society

VOLUME: 125

Page Numbers: 9280-1

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 6

MONTH: Aug

YEAR: 2003

Effect of catenation on protein folding stability. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503056

Effect of catenation on protein folding stability. Keywords Mesh Terms:

KEYWORDS: Proteins

MESH TERMS: chemistry

Chemical & Substance for Abstract: Effect of catenation on protein folding stability. Information

Substance Name: catenane

Registry Number: 0

Grant and Affiliation Information for Effect of catenation on protein folding stability.

AFFILIATION: Department of Physics and Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida 32306, USA. hxzhou@csit.fsu.edu

Country: United States

AGENCY: United States NIGMS

GRANT: GM58187

ACRONYM: GM

MEDLINETA: J Am Chem Soc

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