Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment.

Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment. Research Abstract Details 

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Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment. Abstract Text:

Y Imai,A Fukuzawa,M Watanabe,

The effect of blending tricalcium phosphate (TCP) on hydrolytic degradation of a new type of poly(L-lactic acid)/poly(ethylene:hexamethylene/sebacate) block polyester (60: 40 wt%) was studied. 100- and 250-microm film specimens blended with 0, 10, and 30 wt% TCP were immersed in phosphate buffered saline (pH 7.4) at 37 degrees C for up to 80-104 weeks. At appropriate intervals, water absorption, dry and wet tensile strength, molecular weight, and thermal properties of the specimens were measured by weighing, tensile strength testing, size exclusion chromatography, and differential scanning calorimetry, respectively. Some samples were characterized by 1H NMR spectroscopy. Blending of TCP with the block polyester was effective in retarding degradation. The blended TCP was thought to retard degradation for the most part by neutralizing the lactic acid oligomers produced by hydrolysis of the poly(lactic acid) part during the initial stage of degradation.

Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment. Publishing Authors By Initials

Y Imai,A Fukuzawa,M Watanabe,

For similar macromolecular substances: polymers research abstracts see: macromolecular substances: polymers research

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Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biomaterials science. Polymer edition

VOLUME: 10

Page Numbers: 773-86

Journal Abbreviation:

ISSN: 0920-5063

DAY: 20

MONTH: 02

YEAR: 1999

Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment. Information

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LANGUAGE: eng

NlmUniqueID: 9007393

Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment. Keywords Mesh Terms:

KEYWORDS: Polymers

MESH TERMS: chemistry

Chemical & Substance for Abstract: Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment. Information

Substance Name: dicalcium phosphate anhydrous

Registry Number: 7757-93-9

Grant and Affiliation Information for Effect of blending tricalcium phosphate on hydrolytic degradation of a block polyester containing poly(L-lactic acid) segment.

AFFILIATION: Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Japan.

Country: NETHERLANDS

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MEDLINETA: J Biomater Sci Polym Ed

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