Effect of alpha tocopheryl succinate on cyclic AMP-dependent protein kinase activity in murine B-16 melanoma cells in culture.
Effect of alpha tocopheryl succinate on cyclic AMP-dependent protein kinase activity in murine B-16 melanoma cells in culture. Research Abstract Details
d-Alpha tocopheryl succinate (vitamin E succinate), which inhibited growth and survival, and induced differentiation in murine B-16 melanoma cells in culture, increased adenosine 3',5'cyclic monophosphate-(cAMP)-dependent protein kinase (PK) activity without increasing the cellular cAMP level. Prostaglandin (PG)A2, which produced changes in melanoma cells similar to those produced by vitamin E succinate, also increased cAMP-dependent PK activity without changing the intracellular level of cAMP.
Effect of alpha tocopheryl succinate on cyclic AMP-dependent protein kinase activity in murine B-16 melanoma cells in culture. Publishing Authors By Initials
Effect of alpha tocopheryl succinate on cyclic AMP-dependent protein kinase activity in murine B-16 melanoma cells in culture. Journal Published:
PUBLICATION TYPE: Research Support, U.S. Gov't,
Journal: Cancer letters
VOLUME: 39
Page Numbers: 129-36
Journal Abbreviation: Cancer Lett.
ISSN: 0304-3835
DAY: 19
MONTH: Mar
YEAR: 1988
Effect of alpha tocopheryl succinate on cyclic AMP-dependent protein kinase activity in murine B-16 melanoma cells in culture. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 7600053
Effect of alpha tocopheryl succinate on cyclic AMP-dependent protein kinase activity in murine B-16 melanoma cells in culture. Keywords Mesh Terms:
KEYWORDS: Vitamin E
MESH TERMS: pharmacology
Chemical & Substance for Abstract: Effect of alpha tocopheryl succinate on cyclic AMP-dependent protein kinase activity in murine B-16 melanoma cells in culture. Information
Substance Name: Protein Kinases
Registry Number: EC 2.7.1.37
Grant and Affiliation Information for Effect of alpha tocopheryl succinate on cyclic AMP-dependent protein kinase activity in murine B-16 melanoma cells in culture.
AFFILIATION: Department of Radiology, College of Medicine, University of Colorado Health Sciences Center, Denver 80262.
Country: NETHERLANDS
AGENCY: United States NCI
GRANT: CA-40619
ACRONYM: CA
MEDLINETA: Cancer Lett
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