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Early pituitary follicle stimulating hormone response to gonadotrophin releasing hormone in ewes.

Early pituitary follicle stimulating hormone response to gonadotrophin releasing hormone in ewes. Research Abstract Details 

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  • Early pituitary follicle stimulating hormone response to gonadotrophin releasing hormone in ewes. Abstract Text:

    l n kanchevL N Kanchev,b m stankovB M Stankov,h dobsonH Dobson,

    The object of our experiments was to characterize the response of plasma follicle stimulating hormone (FSH) within minutes of an i.v. injection of high or low doses of gonadotrophin releasing hormone (GnRH), especially in relation to contemporary changes in luteinizing hormone (LH) concentrations. In the deep anoestrous period (June), three intact ewes and two ovariectomized ewes were injected with 1 mug synthetic GnRH followed 2 h later by a second identical injection. A week later, the same regimen was repeated with the same sheep but with 50 mug GnRH after an interval of 5 h 20 min. Blood samples were collected every 15 sec for 15 min after each injection (early release), then at longer intervals (main release) till the next treatment, followed by sampling for a further 6-h period after the second treatment. FSH was released as soon as the second minute after GnRH injection in all ewes. The mean pituitary FSH response, during this early release, in intact and ovariectomized ewes was similar after either 1 or 50 mug GnRH. However, the main release was less pronounced in the ovariectomized sheep and was not stimulated after the second treatment in all sheep. Three other ewes were injected with 40 mug GnRH and sampled every 15 sec for seven, 6-min periods during the period of release to compare FSH and LH secretion. The profiles reflected a similarity in sensitivity and responsiveness to GnRH, especially soon after GnRH injection. Increases in both hormones were formed by several grouped associated spikes. It is suggested that a readily releasable pool of FSH exists in the ewe. There are probably differences in the mechanisms of synthesis and/or release between pituitary FSH and LH.

    Early pituitary follicle stimulating hormone response to gonadotrophin releasing hormone in ewes. Publishing Authors By Initials

    ln kanchevLN Kanchev,bm stankovBM Stankov,h dobsonH Dobson,

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    Early pituitary follicle stimulating hormone response to gonadotrophin releasing hormone in ewes. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Theriogenology

    VOLUME: 28

    Page Numbers: 435-44

    Journal Abbreviation: Theriogenology

    ISSN: 0093-691X

    DAY: 26

    MONTH: Oct

    YEAR: 1987

    Early pituitary follicle stimulating hormone response to gonadotrophin releasing hormone in ewes. Information

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    LANGUAGE: eng

    NlmUniqueID: 421510

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    Grant and Affiliation Information for Early pituitary follicle stimulating hormone response to gonadotrophin releasing hormone in ewes.

    AFFILIATION: Institute of Biology and Immunology of Reproduction, 73, Lenin Boulevard, Sofia 1113, Bulgaria.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Theriogenology

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